
<p>Today, we’ll hear about:</p> <p>• A young business owner questioning whether to work fewer hours</p> <p>• Dave’s advice on profit sharing for small businesses</p> <p>• How Dave would handle marketing for a small business</p> <p>• A woman wondering how to protect her marriage when going into business with her husband</p> <p> </p> <p>Next Steps:</p> <p>· 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us</p> <p>· 📚 Learn about the EntreLeadership System™: https://ter.li/system-p</p> <p>· 💻 Get EntreLeadership Elite™ for your business: https://ter.li/elite-p</p> <p>· ✉️ Sign up to receive tactic...

<p>We love to hear from our listeners. Send us a message. </p><p>On this week's episode of the Business of Biotech, we're speaking with Thomas von Erlach, Ph.D., Cofounder and CEO at Vivtex, a company spun out of the Langer Lab at MIT that's focused on developing orally available biologics. The company announced a deal in late February '26 with Novo Nordisk for up to $2.1 billion to develop next-gen oral drugs for obesity and diabetes, bringing the total number of Vivtex's partnerships to 10. Thomas shares his experiences working in the lab with Dr. Robert Langer, Ph.D...

[Frank Wahlig im Gespräch mit Axel Göhring]<br /><br />Welcher Weltuntergang darf es denn sein? Die Erde brennt, und die Menschheit fackelt ab. Der Meeresspiegel steigt, und sintflutgleich sterben die Menschen in den Küstenregionen. Das Klima wandelt sich. Das tut es immer schon. Aber stimmen denn die Alarmmeldungen der Klimaaktivisten, stimmen die Computermodelle, die einen menschengemachten Klimawandel belegen wollen? Frank Wahlig spricht mit dem Naturwissenschaftler Dr. Axel Göhring über die Liebe der Deutschen zum Weltuntergang und darüber, welche brillanten Geschäfte sich damit einfädeln lassen.

In this conversation, Peter discusses the various technological advancements and partnerships within the Cardano ecosystem, focusing on how these developments will contribute to mass adoption and enhance the overall functionality of the blockchain. He highlights the importance of scaling solutions, interoperability, liquidity, data integrity, and privacy, while also emphasizing the need for transparency through analytics.<br /><br /><br /><br /><br /><b>Takeaways</b><br />Cardano is building a comprehensive layer stack for mass adoption.The EUTXO model provides predictable fees and transaction reliability.Laos will significantly enhance Cardano's transaction capacity.Layer zero will improve cross-chain interoperability.USDCX will facilitate liquidity...











Es begann vor fünfzehn Jahren in einer Klitsche in Berlin. Sie sammelten Daten. Ihr Beruf: Friedhofsgärtner der überflüssigen Daten. Heute beschäftigt Emanuel Böminghaus 200 Spezialisten in Berlin und in Bangalore, Indien. Das Geschäft weitet sich aus, viele DAX-Konzerne geben dem Unternehmen Avendata ihre alten, überflüssigen Datensätze zum Aufbewahren. Und als Unternehmer weiß Böminghaus, dass nicht nur Daten schnell sind, sondern auch Leistungsträger und Unternehmen.

<p>Send a text</p><p>Uncertainty weighs on risk appetite; crypto winter persists. Stocks try to find<br/>their footing ahead of Wednesday’s Nvidia earnings. Trump’s State of the<br/>Union in focus as reports point to an imminent strike on Iran. Dollar’s rally<br/>pauses; gold and oil consolidate after gains.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the ti...

<p>Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and Lisp, the MongoDB and Ruby decisions Stripe still lives with 15 years later, why he'd spend even more time on API design if he could do it over, and whether AI is actually showing up in economic productivity data. This episode originally aired on Cursor's podcast.</p> <p> </p> <p>Resources: </p> <p>Follow Patrick Collison on X: https://twitter.com/patrickc</p> <p>Follow Michael Truell on X: https://twitter.com/mntruell</p> <p>Fo...

<p>We love to hear from our listeners. Send us a message. </p><p>On this week's episode of the Business of Biotech, we're speaking with Kenneth Galbraith, CEO and Board Chair at Zymeworks, a biotech developing multispecific therapies internally and through partnerships with companies including Jazz Pharmaceuticals and BeOne Medicines (formerly BeiGene), J&J, Merck, Daiichi Sankyo, and GSK. Ken talks about Zymeworks' shift to a royalty model for development funding and value creation, lessons learned from platform deals and cross-border R&D, the benefits of strong royalty agreements and backloaded milestone payments over headline upfronts, and industry dynamics...

<p>Bloomberg's Odd Lots hosts Joe Weisenthal and Tracy Alloway speak with David George, general partner at a16z and head of the firm's growth fund, about why $5 trillion in tech market cap now sits in the private markets, how that figure has grown 10x in a decade, and what it means for founders, employees, and investors. They also cover SPVs, tender offers, the collapse of legacy software valuations, and why AI companies may be speed-running the path to public markets. This episode originally aired on Bloomberg's Odd Lots podcast.</p> <p> </p> <p>Resources:</p> <p>Follow Joe Weisenthal: h...

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<p>Today, we’ll hear about:</p> How to recover after incurring debt and damaging relationships with vendors A business owner looking to maintain company culture with his remote teams Dave’s advice on reversing a bad promotion A dad struggling to hand off the business smoothly to his sons <p> </p> <p>Next Steps:</p> 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us 🚢 Set Sail with Dave Ramsey! Book your cabin today: https://ter.li/s8xnyo 📚 Learn about the EntreLeadership System™: https://ter.li/system-p 💻 Get EntreLeadership Elite™ for your business: ht...

Der Bürger und Wähler atmet erst einmal tief durch, das beruhigt. Aufregend wird das neue Jahr so oder so werden. Also Ruhe und Entschlossenheit, bevor es in den kommenden Monaten turbulent werden wird. Es soll ein Ausblick auf das neue Jahr werden, und ist eine Abrechnung mit der Politik eines zögerlichen und zaudernden Kanzlers geworden. Frank Wahlig spricht mit dem Unternehmer, Energie- und Politexperten Marc März. Er ist von einer fast gelassenen Hoffnungslosigkeit, was Gutes in diesem Jahr betrifft, aber meint auch: Irgendwann werde sie kommen müssen, die Veränderung.<br /><br /><br />

<p>Send a text</p><p>Gold and oil jump amid fears US will attack Iran even as nuclear talks<br/>progress. Dollar climbs to two-week high as Fed minutes confirm hawkish<br/>tilt. Wall Street edges higher on easing AI fears, Walmart earnings eyed.<br/>Aussie and kiwi outperform on rate hike bets.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time...

<p>If sales are up but the bank account says otherwise, something’s off. In this episode, you’ll learn the difference between revenue, profit, and cash flow—and the practical steps leaders use to fix cash flow problems for good.</p> <p><br></p> <p>Next Steps:</p> 📊 Download the free EntreLeader’s Guide to Business Finances to discover the key money practices of successful small businesses: https://ter.li/4th9bw 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us 📚 Learn about the EntreLeadership System™: https://ter.li/system-p 💻 Get EntreLeadership El...

<p>On today’s episode, we welcome Mike Glick, CEO of NIMA Partners — the company behind the next-generation portable gluten sensor designed to deliver real-time food testing with 99% accuracy across major gluten sources. With growing demand for food transparency and consumer diagnostics, NIMA is helping reshape how people with celiac disease and gluten sensitivity confidently navigate what they eat.<br> Mike’s journey to leading NIMA Partners has been rooted in a career focused on improving nutrition, safety, and health outcomes. Prior to joining NIMA, he led and scaled multiple food allergy and nutrition startups including Goode Health, Else Nutrition, and Sp...

<p>In this episode from WSJ Invest Live, Andy Serwer speaks with Katherine Boyle, general partner at a16z, about the American Dynamism practice she helped launch four years ago. They discuss why saying "America" out loud stunned Silicon Valley in 2022, how Russia's invasion of Ukraine changed everything, and what it means to invest in companies that support the national interest.</p><p> </p><p> </p> <p><p>Stay Updated:</p><p>Find a16z on YouTube: YouTube</p><p>Find a16z on X</p><p>Find a16z on LinkedIn</p><p>Listen to the a16z Show on...

<p>Post-shutdown recovery is one item carrying over from calendar year 2025 into 2026 and the chance of another funding stoppage happening on Jan. 30 is not zero percent.</p><p>That here-and-now is the starting point of this episode where Stephanie Smith, GovCon industry senior analyst and valuation services director at RSM, takes us through some of the major themes and talking points that will shape the ecosystem in 2026.</p><p>How do we define the “non-traditional contractor” and what do their prospects look like? As Steph tells our Ross Wilkers, technical definitions and terms for talking about these companies are moving targ...

<p>Most years of a presidential transition result in some adjustments by the government contracting community as a new administration settles in, but 2025 presented more variables to GovCon than ever before.</p><p>Stephanie Kostro, president of the Professional Services Council, fields many questions from PSC’s member companies about what is happening across the ecosystem. Kostro joins Nick and Ross for this episode to unpack some that were answered in 2025 and others that remain unanswered for 2026, including the prospects of a second shutdown following the last one.</p><p>How the Department of Government Efficiency’s influence remains over GovC...

<p>Balaji Srinivasan speaks with Dan Wang, author of Breakneck, about China's industrial rise, America's competing strengths in software and finance, and what happens when an engineering state and a lawyerly state collide. The conversation covers manufacturing dominance, the future of the dollar, why both superpowers keep making costly mistakes, and where builders fit into what comes next.</p><p> </p><p>Resources:</p><p>Follow Dan Wang on X: https://twitter.com/danwwang</p><p>Follow Balaji on X: https://twitter.com/balajis</p><p>Subscribe to Network State Podcast: https://www.youtube.com/@nspodcast</p> <p><p>Stay Up...

<p>Data labeling refers to the practice of tagging and identifying raw data in order to add meaningful context, of which U.S. government agencies openly admit they struggle with and ask industry for help in.</p> <p>Peter Kant, founder and chief executive of Enabled Intelligence, started the company in March 2020 to specialize in data labeling work that also relies on continuous training and retraining of artificial intelligence models.</p> <p>Kant joins for this episode to explain how Enabled Intelligence tailors large language models for use in national security environments where the out-of-the-box tools are not quite ready...

<p>On today’s episode, we welcome Jenn Krouse, CEO and Founder of AUNU — a skincare brand built around the transformative power of medical-grade Mānuka honey. After helping scale iconic brands like Tory Burch, WeWork, and Victoria Beckham Beauty — where she was part of the founding executive team that grew the business to over $100M — Jenn set out to build a company rooted in trust, clinical efficacy, and the intelligence of nature.<br />AUNU was inspired by both professional insight and personal experience. Growing up between Korea and Japan, Jenn was introduced early to the healing properties of Mānuka honey...

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<p>We love to hear from our listeners. Send us a message. </p><p>On this week's episode of the Business of Biotech -- on location at the J.P. Morgan Healthcare Conference -- we're speaking with Ron Cooper, CEO and Board Member at enGene, to unpack how he scaled Albireo from a small research shop to a global commercial company, and why he’s now betting on nonviral gene therapy at enGene to help patients with non-muscle invasive bladder cancer keep their bladders. Cooper talks about the importance of keeping development, financing, and hiring in sync as biotech companies gr...

<p>If your business only works when you’re working, something has to change.</p> <p>In this episode, you’ll learn how to regain margin, hand off responsibility the right way, and</p> <p>build a business that keeps moving forward even when you step away.</p> <p><br></p> <p>Next Steps:</p> 🎥 Watch our video 3 Questions That Could Save Your Business From Going Broke 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us 📚 Learn about the EntreLeadership System™: https://ter.li/system-p 💻 Get EntreLeadership Elite™ for your business: https://ter.li/elite...

<p>We love to hear from our listeners. Send us a message. </p><p>On this week's episode of the Business of Biotech, Nick Manusos, CEO at Kenai Therapeutics, talks about his experiences building cell therapy spinouts from FujiFilm Cellular Dynamics, learning from big pharma decision-making processes, and dosing the first patient with Kenai's allogeneic neuron replacement cell therapy for Parkinson's disease. Nick also talks about funding an early-stage cell therapy company and forging key manufacturing and therapy administration partnerships. </p><p>Access this and hundreds of episodes of the <b>Business of Biotech videocast</b> under the <b>Business o...

<p>Humans in the loop are, in theory, supposed to be as much a part of all conversations surrounding the use of generative artificial intelligence tools as a way to safeguard against major mistakes.</p> <p>But as GovCon attorney David Timm has found out, errors showing misuse of the technology are starting to come up in bid protests and other legal rulings that show what can go wrong when relying on the tech too much.</p> <p>Timm, a partner at the law firm Burr & Forman, joins our Ross Wilkers for this episode to share his findings from those...

<p>MFS, a big lender based in London, has been making risky loans and is in the British equivalent of bankruptcy. Now, investors are buying up U.S. government bonds, and lenders are pulling back from the riskiest parts of the private credit markets. Is there a bigger pattern here? We'll discuss. Then, Anthropic is rejecting the Pentagon’s demands for unrestricted use of its technology, and we'll hear how business is going for a Main lobster fisherman.</p>

<p>Send a text</p><p>Tensions continue to build over Iran as Trump sets deadline for nuclear<br/>deal. Dollar climbs to one-month peak, eyes US GDP and PCE inflation<br/>data. Oil surges to 6-month high but gold can barely grip onto $5,000<br/>handle. Yen flounders again, equities trade mixed.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time of publication...

<p>Send a text</p><p>Slow start to the week; China and the US on holiday today. Busy event calendar ahead, with a potential Supreme Court decision on Friday. US equity weakness in the spotlight; dollar benefits from lingering ‘risk off’ sentiment. Dollar/yen slide pauses; Japanese sovereign yields drop after weak GDP report.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time...

<p>In this feed drop from the Internet History Podcast, host Brian McCullough speaks with Chris Dixon, general partner at a16z, about his path from 1980s hobbyist programmer to one of the most prominent venture capitalists in tech. Chris traces his career from quantitative finance to founding SiteAdvisor, cofounding Founder Collective, starting an early machine learning company, and eventually building a16z's crypto practice from the ground up. They also discuss his framework for spotting unconventional investments, the current state of crypto regulation, and why New York is becoming a serious tech hub.</p> <p> </p> <p>Resources:</p> <p...

<p>Consolidation and “common goods and services” dominate the discussion around how the federal government wants to revamp its contracting functions, including moves to put the General Services Administration at the center of it all.</p><p>Leo Alvarez and Dylan Schreiner, respectively principal and GovCon senior manager at Baker Tilly, are fielding many questions from industry clients on what this landscape looks like and how to map their business strategies to it.</p><p>In this episode, Leo and Dylan walk our Ross Wilkers through some of the big-ticket vehicles to watch in 2026 and how they help illustrate the gove...

Summary<br />In this episode, Peter dives into the current state of the crypto landscape, focusing on the Midnight and Cardano Blockchains. He discusses the implications of the recently passed Genius Act, which allows for stablecoin rewards, and highlights the ongoing struggle between banks and crypto companies over regulatory control. Peter emphasises the need for a level playing field where both sectors can thrive, particularly in the realm of stablecoins. He also shares insights on the price trends of the Midnight token, upcoming developments, and his plans to attend meetups in Japan to engage with the community and learn more...

Er hat sie studiert und ihr zugehört. Der Frau, die „Wir schaffen das“ sagte und meinte: Viel Spaß mit dem Ärger. Der österreichische Publizist und Bestsellerautor Gerald Grosz meint, Angela Merkel hat die muslimische Massenmigration 2015 gewollt, vielleicht sogar beabsichtigt. Die deutsche Nation, die österreichische Nation sei ihr nichts wert. Im Gegenteil – Merkel wolle die Auflösung der Nationen, so Grosz im Gespräch mit Frank Wahlig. (Wiederholung vom 9. September 2025)

<p>Send a text</p><p>Equities mixed despite stellar Nvidia earnings as AI doubts persist. Tariff uncertainty, hawkish Fed and BoJ could also be dragging on sentiment. Dollar marginally weaker as yen recovers from lows. Gold and oil edge up ahead of fresh US-Iran nuclear talks.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time of publication and may change. Please check...

<p>The private credit market has grown fivefold since 2008 — it’s somewhere near the $2 trillion-mark globally. In this episode, we explain why policies aimed at alleviating the Great Recession triggered an explosion of non-bank lenders, and why their loans are riskier for the economy than traditional loans. Plus: Analysts expect wholesale inflation cooled a bit in January, retailers fret over a late-winter slump, and stock market predictions are sort of like baking a cake. </p><br/><p>Every story has an economic angle. Want some in your inbox? Subscribe to our daily or weekly newsletter.</p><br/><p>Marketplace is more t...

<p>On today’s episode, we welcome Heather Morgan, CEO of Neurobiologix — the science-driven wellness company using nutrigenomics to personalize supplements and help people get to the root cause of their health challenges.<br />Neurobiologix is redefining how we think about supplementation. Instead of generic, one-size-fits-all products, the company pairs advanced genetic testing with practitioner-grade formulas designed to support immune, cognitive, and neurological health based on an individual’s DNA. Neurobiologix represents an evolution toward precision, personalization, and evidence-based care.<br />In this episode, Heather shares how Neurobiologix blends genetics, technology, and clinical expertise to deliver smarter wellness solutions, why person...

<p>On today’s episode, we welcome Joey Zwillinger, Co-Founder and CEO of Biologica — a science-backed wellness brand redefining hormonal health for women at every life stage. Best known for co-founding Allbirds and leading the company through its IPO, Joey is now applying his category-creation expertise to a new frontier: women’s wellness. Built alongside his wife Elizabeth and inspired by her lived experience navigating decades of hormonal shifts, Biologica was created to address a major gap in the supplement industry — the lack of targeted, stage-specific support for women.<br> Joey’s path to launching Biologica reflects a career dedicated to purpose...

<p>From the BBC World Service: First up, British manufacturer Dyson settles a lawsuit filed against it by 24 migrant workers, and the Premier League says it's launching its own streaming service. And while David Brancaccio and the team will continue to share the economic news you need each weekday morning, today marks the final edition of the "Marketplace Morning Report" produced by the BBC World Service. Host Leanna Byrne reminisces about some of the show’s biggest global news stories from over the years.</p>

<p>Today, we’ll hear about:</p> A business owner who added $1.5 million in debt and doesn’t know what to do next Why leaders must stop doing the work to grow the business Why Dave Ramsey recommends starting your own business versus purchasing an existing one How debt increases risk even when growth looks successful <p><br></p> <p>Next Steps:</p> 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us 📚 Learn about the EntreLeadership System™: https://ter.li/system-p 💻 Get EntreLeadership Elite™ for your business: https://ter.li/elite-p ✉️ Sign up to receive tact...

<p>In his Nov. 7 address to industry, Defense Secretary Pete Hegseth laid out what the U.S. military wants from its contractors and wholesale changes the Pentagon is carrying out to make agile acquisitions a reality.</p><p>Lauren Williams, senior editor at Defense One who covers the industrial base, was there in-person and joins our Ross Wilkers for this episode to walk through those structural changes that prior Defense Department leaders have spoken about for years.</p><p>One major theme of that dialogue has been DOD’s desire to have more commercial technologies, which has been easier said th...

In this conversation, the hosts discuss the innovative game Ascent Rivals, a fusion of racing, combat, and strategy, developed with a focus on traditional gaming experiences. The developers share their backgrounds in game development and esports, emphasising community engagement and organic growth during the alpha phase. They explore funding strategies, integrating Web3 elements, and the technical aspects of building on the Cardano blockchain, aiming to create a game that appeals to both traditional and Web3 gamers.<br /><br />Takeaways<br />Ascent Rivals is a fusion game combining racing, combat, and strategy.The development team has a strong background in traditional...

Warum glauben viele deutsche Medien, dass die Sanktionen gegen Russland ein voller Erfolg sind? Das „Handelsblatt“ frohlockt, dass das ukrainische Wirtschaftswachstum am russischen Wirtschaftswachstum vorbeizieht. Seriöser ist eine Erhebung des Russischen Verbands der Industriellen und Unternehmen, die sagt: Nur 4 Prozent der teilnehmenden russischen Firmen schätzen die Geschäftslage im Land noch als gut ein. Ein Drittel der Betriebe klagt über eine rückläufige Nachfrage. Lag das Wirtschaftswachstum 2023 noch bei 4,08 Prozent und im Jahr 2024 sogar bei 4,34 Prozent, so fiel es im Jahr 2025 auf 0,61 Prozent. Wie funktioniert Russlands Wirtschaft, und wie ist es um sie tatsächlich bestellt?

<p>Hard conversations aren’t optional—they’re part of the job. In this episode, you’ll learn how to handle the five types of difficult conversations leaders face with clarity and confidence—so you can lead decisively instead of tiptoeing around problems.</p> <p><br></p> <p>Next Steps:</p> 🎥 Watch our video The 3 Mistakes People Make in Hard Conversations (and How to Avoid Them): https://www.youtube.com/watch?v=UBsV1vHu7rY 📋 Get the framework for addressing your difficult employees: https://ter.li/ravdz3 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://te...

<p>Pressure points on defense companies from their Pentagon customer to invest more and do business differently than before are coming from multiple levels of leadership, including President Trump himself.</p><p>Lauren Williams, business editor at our partner publication Defense One, canvasses the perspectives and opinions of industry pros on that matter to help put together the Defense Business Brief newsletter that goes out every Monday.</p><p>Lauren joins our Ross Wilkers for this episode to break down those different pressure points, including Trump’s executive order barring companies from stock repurchases and issuing dividends until they invest mo...

<p>On today’s episode, we welcome Kayse Gehret, Founder and Microdosing Guide behind Microdosing for Healing — a global education platform bringing clarity, intention, and responsibility to the rapidly growing conversation around microdosing.<br />With nearly 30 years of experience in the healing arts, Kayse has supported more than 1,400 individuals across 30+ countries. Her work stands apart for its grounded, nervous-system–informed approach, emphasizing preparation, integration, and discernment over hype or quick fixes. Rather than treating microdosing as a trend, Kayse frames it as a deeply personal practice rooted in safety, self-awareness, and lived experience.<br />In this episode, Kayse breaks down what m...

[Klaus-Rüdiger Mai mit Thilo Schmitz]<br /><br />Seit Trumps Eingreifen in Venezuela und der Entmachtung von Diktator Nicolás Maduro ist Venezuela in aller Munde. Über Trumps Aktion reden alle, über die Lage in Venezuela, über das Leben der Bürger, die Lebensverhältnisse und die Situation der Wirtschaft niemand. Laut einem Bericht der UN von 2024 leben fast 82 Prozent der Venezolaner in Armut, 53 Prozent davon in extremer Armut. Im Jahr 2018 betrug die Inflationsrate 1.000.000 Prozent und ähnelte damit der Lage in Deutschland 1923. Unser Gast zu diesem Thema ist Thilo Schmitz, der als Unternehmer in Venezuela tätig ist.

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This conversation covers the latest developments in the crypto space, focusing on the Cardano ecosystem, particularly the launch of USDC, liquidity improvements, and the innovative Midnight Network. It discusses the importance of user experience in crypto transactions, the emergence of projects on Midnight, and the challenges posed by Maximal Extractable Value (MEV) bots. Additionally, it highlights partnerships and the future of Cardano, including hardware preparations for becoming a Midnight validator.<br /><br /><b>Takeaways</b><br />The Korean government accidentally compromised a seed phrase.USDC is now available on the Cardano ecosystem, enhancing liquidity.Cross-chain capabilities are improving for Cardano...

<p>On today’s episode, we welcome Raj Alva, Co-Founder of Whiskey JYPSI — the award-winning whiskey brand redefining modern American whiskey through craft, culture, and storytelling.<br />Raj is a serial entrepreneur, brand architect, and investor known for building culturally resonant consumer brands that thrive during moments of disruption. With Whiskey JYPSI, he saw white space in a category steeped in tradition and chose to approach it differently — focusing on blending excellence, creative freedom, and emotional connection rather than owning a distillery or following conventional playbooks.<br />In this episode, Raj shares how Whiskey JYPSI was built by leaning into uncert...

<p>Send a text</p><p>Trump orders attack on Iran as Middle East descends into chaos. Oil shoots higher despite OPEC+ increasing output more than expected. Investors flock to gold, dollar and Swiss franc for safety as stocks tumble.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time of publication and may change. Please check our Risk Disclosure for an up to...

<p>a16z's Martin Casado and Sarah Wang join Latent Space hosts Alessio Fanelli and Swyx to discuss what makes this AI investment cycle unlike anything in the history of venture capital. They cover why the lines between venture and growth, apps and infrastructure are blurring, how frontier model companies can raise more than the aggregate of everyone built on top of them, and why the industry-wide gap between perception and reality has never been wider.</p> <p> </p> <p><p>Stay Updated:</p><p>Find a16z on YouTube: YouTube</p><p>Find a16z on X</p><p>F...

<p>We love to hear from our listeners. Send us a message. </p><p>On this week's episode of the Business of Biotech, Jared Bauer, Cofounder and CEO at Seek Labs, talks about his adventures in company turnarounds, and setting up Seek Labs to improve patient diagnoses and to discover and develop new treatments for infectious diseases. Jared explains the technology convergence that was needed to build Seek Labs' AI diagnostic and CRISPR-based therapeutics platform, an African Swine Fever proof-of-concept study that reduced viremia in pigs, mapping pathogens for rapid target design, and engaging with the FDA and global regulatory...

<p>Paramount Skydance appears to have won the bidding war for Warner Bros. Discovery. Paramount raised its offer, and rival Netflix refused to match it, saying the deal is “no longer financially attractive.” The merger still has to be approved by federal regulators. We'll learn more, then dig into the current state of streaming services. And later in the program, roughly half of high schoolers planning to go to college are using AI tools in their search.</p>

<p>Commercial technology is front-and-center of everyone’s mind across the public sector ecosystem these days, but history shows that agencies have moved slow on the acquisition and adoption fronts here.</p><p>Sheila Duffy, founder and chief executive of Greystones Group, views these efforts as grounded in collaboration as customer and contractor both have to agree on the roadmap for development and implementation.</p><p>Duffy joins our Ross Wilkers for this episode to go over keys for good collaborations with agencies on rolling out modern tools and how Small Business Innovation Research programs can be a pathway to ac...

<p>On today’s show, we’re taking a trip to the Green Mountain State for an up close look at one of Vermont’s most pressing economic issues: housing. Kimberly is joined by Carly Berlin, housing reporter for VTDigger and Vermont Public, to talk about the factors driving Vermont’s housing crisis and how solutions, like a catalog of pre-approved home designs, could help fix it. Plus, are you more of a Vermont cheddar or a Ben & Jerry’s type of person?</p><br/><p>Here’s everything we talked about today:</p><br/>"Vermont Housing Needs Assessment" from the State of...

[Frank Wahlig im Gespräch mit Raphael Störchli]<br />Das typische Geklappere ist zu einem nostalgischen Geräusch geworden. Im Ohr ist es einem noch, aber im praktischen Leben spielt die Schreibmaschine keine Rolle mehr. Der Schweizer Raphael Störchli repariert diese feinmechanischen Wunderwerke und lebt gut davon. Was macht die Schreibmaschine in Benutzung mit dem Nutzer, wie verändert ein solches Schreiben die Gedanken? Ein Gespräch über Schreiben, Denken und Tippen.

<p>The spring of 2024 was a turning point for Nightwing, when the business separated out of its then-parent RTX to become a standalone company focused on cybersecurity and intelligence solutions.</p><p>Chris Jones joined Nightwing later that fall as chief technology officer following service as the CIA’s associate deputy director for science and technology. Jones joins for this episode to put into perspective how Nightwing has sought to carve out its own path in the market and priority areas for the company going forward.</p><p>In talking with our Ross Wilkers, Jones also explains the role of co...

<p>We love to hear from our listeners. Send us a message. </p><p>On this week's episode of the Business of Biotech we speak with Monika Sumra, Ph.D., about how leadership, culture, and performance emerge from the environment and conditions inside an organization. Dr. Sumra, Founder and Managing Partner at Bunka, Inc., a management consulting firm and advisor to manufacturing-based organizations globally, explains how anthropology, CPIs, and rapid ethnography make culture measurable and operations faster, safer, and more reliable. Deploying a unique lens built on biosocial anthropology, she offers guidance on creating environments for sustainable performance in the...

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<p>Moonshots host Peter Diamandis speaks with Ben Horowitz, cofounder and general partner at a16z, alongside regular cohosts Salim Ismail, Dave Blundin, and Dr. Alexander Wissner-Gross, about whether AI can or should be paused, what happened when Horowitz told a Biden administration official that regulating AI means regulating math, why crypto is the natural money for AI agents, and why the gap between AI capability and societal adoption may be wider than people think. This episode originally aired on Peter Diamandis's Moonshots podcast.</p> <p> </p> <p>Follow Peter H. Diamandis on X: https://x.com/PeterDiamandis</p> <p>F...

<p>American Systems opened for business in 1975 and transitioned to an employee stock ownership plan 15 years later, a model that makes it one of the market’s largest 100% ESOP companies.</p><p>CEO John Steckel joins for this episode to help mark American Systems’ 50th anniversary and explains some moves it has made this year to set the company up for the next 50, including its largest-ever acquisition.</p><p>In talking with our Ross Wilkers, Steckel lays out what the purchase of Epsilon brings to American Systems and larger trends in managed services that led to the transaction. Secured data cent...

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Go behind the scenes with the team building Atlas, a game-changing DeFi protocol on Cardano and Midnight that unlocks "trapped" staking rewards through yield tokenization. Learn how they are partnering with Midnight and Iagon to bring institutional-grade privacy and liquid yield strategies to everyone in 2026.<br /><br />Chapters<br />00:00 Introduction to Atlas and the Guests<br />03:04 Backgrounds in Crypto and Cardano<br />06:06 Understanding Atlas and Its Purpose<br />09:10 Yield Tokenization Explained<br />11:45 Future of Atlas and Real World Assets<br />15:02 Partnerships and Collaborations<br />18:06 Development Timeline and Community Engagement<br /><br /><br />DISCLAIMER: This content is for informational and educational...

This conversation explores the introduction of USDCX into the Cardano ecosystem, detailing the implications of the Circle Cross-Chain Transfer Protocol (CCTP), the bridging process, and strategies to attract liquidity to the ecosystem. It also acknowledges community contributions, discusses Wanchain's role in facilitating cross-chain transfers, and raises important questions about treasury funds and profit sharing. The discussion concludes with an optimistic outlook for Cardano's future.<br /><br /><b>Takeaways</b><br />USDCX is now available on the Cardano ecosystem.The CCTP uses a burn-and-mint model for asset transfers.Bridging assets is simplified through a new protocol.Attracting liquidity requires competitive rewards...

<p>We love to hear from our listeners. Send us a message. </p><p>On this week's episode of the Business of Biotech, we're speaking with Cindy Perettie, Executive Vice President and Global Head at Kite Pharma, a Gilead-owned company focused on curing cancer with cell therapies. Perettie talks about scaling cell therapies in the community setting, global manufacturing strategy, preparing for the launch of late-stage development programs in lymphoma and multiple myeloma, and working with partners like Arcellx. She also discusses cell therapy funding cycles and big pharma, the autologous versus allogeneic divide, why in vivo CAR-T therapies could...

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<p>On today’s episode, we welcome Victoria Eisner, Co-Founder and CEO of Hair Cultivated and the original founder of Glamsquad — the trailblazing on-demand beauty service that transformed how women access professional hair, makeup, and nail care. Known for building brands that sit at the intersection of luxury, science, and technology, Victoria is once again stepping into white space — this time to address an issue impacting millions of women: hair loss.<br />After redefining convenience in beauty with Glamsquad, Victoria turned her focus toward a category that has long lacked both innovation and empathy. With Hair Cultivated, she is bridging beauty...

In this conversation, Peter discusses the launch of USDCX, a new stablecoin in the Cardano ecosystem, and its implications for the crypto market. He highlights the innovative features of USDCX, including its auto-conversion capabilities and privacy-preserving technology. The conversation also covers the upcoming Midnight Protocol launch, the significance of Layer Zero integration, and the importance of optimism in the current crypto landscape.<br /><br /><br /><br /><b>Takeaways</b><br />USDCX is a game-changer for the Cardano ecosystem.The Midnight Protocol will enhance privacy and usability.Layer Zero integration connects Cardano to multiple blockchains.USDCX offers seamless asset transfers without...

<p>Now that the Winter Olympics have wrapped up, the Milan Cortina Paralympic Games kick off on March 6. Dozens of athletes will represent Team USA in sled hockey, skiing, wheelchair curling, and snowboarding. But getting to the Olympics or Paralympics is expensive and costs competitors an average of $12,000 a year. For winter athletes in particular, the costs can be even higher. But first: why the FDA is looking to put the brakes on compounded GLP-1s.</p>

<p>Send a text</p><p>Improved risk appetite pushes stocks higher. Focus shifts to Nvidia earnings after US markets close. Trump highlights diplomacy as the main way out of the US-Iran crisis. Gold and oil maintain recent gains; dollar whipsaws.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time of publication and may change. Please check our Risk Disclosure for an up...

<p>Today we’ll hear about:</p> A nephew wondering how to convince his uncle to sell his portion of the business A businessman looking to wisely utilize debt in his business A small business that is dropping the ball with their customer service A business owner whose team regularly leaves him short-staffed <p> </p> <p>Next Steps:</p> 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us 🚢 Set Sail with Dave Ramsey! Book your cabin today: https://ter.li/s8xnyo 📚 Learn about the EntreLeadership System™: https://ter.li/system-p 💻 Get EntreLeadersh...

<p>Send a text</p><p>Fed minutes awaited as traders expect more than two Fed cuts this year. Yen slips, pound trades indecisively after CPIs, kiwi falls after RBNZ. Wall Street recovers on tech rebound, progress in US-Iran talks.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time of publication and may change. Please check our Risk Disclosure for an up to...

<p>Things have felt pretty chaotic in this economy since the Supreme Court struck down President Trump’s signature tariffs last week. On today’s show, Kai Ryssdal joins Kimberly to share his takeaways from the decision and the legal questions surrounding Trump’s new global tariff. Plus, how would tariff refunds actually work?</p>

<p>Today, we’ll hear about:</p> <p>· A leader questioning if he should take a promotion</p> <p>· A son weighing if he should leave his successful business to help save his father’s failing company</p> <p>· Dave’s advice on how to deliver difficult feedback to a team</p> <p>· A business owner considering leaving his business in the hands of his team so he can move to another country</p> <p> </p> <p>Next Steps:</p> <p>· 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us</p> <p>· 📚 Learn about the EntreLeadersh...

<p>We love to hear from our listeners. Send us a message. </p><p>The Business of Biotech was back in San Francisco for the J.P. Morgan Healthcare Conference (January 12 - 15) and this week we sit down with Marc Salzberg, M.D., CEO, CMO, and Board Chair at Airway Therapeutics, a company developing a recombinant version of human surfactant protein D for several respiratory, inflammatory, and infectious diseases including bronchopulmonary dysplasia (BPD), which is currently in Phase 2b/3 trials. Brian talks about why he selected BPD as a lead clinical indication (a disease primarily affecting preterm infants), what he...

Die staatlichen Raumfahrtprogramme haben versagt. Die Eroberung des Weltraums wird privat sein, wie Dr. Rainer Zitelmann in seinem neuen Buch „Weltraumkapitalismus“ ausführt. Private Investoren waren schon immer an der Erforschung des Weltraums beteiligt. Neue private Unternehmen wie Elon Musks SpaceX leisten dabei Großartiges. Der Abbau von Rohstoffen auf Asteroiden oder die Besiedelung des Mars sind möglich. Bedingung dafür ist Privateigentum im All.

In this conversation, Peter discusses the launch of the Midnight Mainnet, focusing on its federated node operators and the importance of privacy and compliance in blockchain technology. He highlights the roles of key players like MoneyGram, eToro, and PairPoint by Vodafone, and emphasises the significance of zero-knowledge proofs in ensuring privacy while maintaining regulatory compliance. The discussion also touches on the future prospects and challenges for Midnight as it transitions from a federated to a decentralised network.<br /><br /><b>Takeaways</b><br />The biggest hurdle to real world adoption of blockchain isn't speed.Midnight focuses on selective disclosure and...

<p>On today’s episode, we welcome Dr. Julie Chung, Co-Founder of T3 — the prestige hair tool brand that pioneered an entirely new category when it launched the original T3 Featherweight hair dryer in 2004. What began as a simple insight — that premium beauty routines deserved equally high-performing hair tools — evolved into a company that has transformed millions of styling routines through thoughtful innovation, elevated design, and a deep commitment to hair health.<br />Dr. Chung’s journey is anything but traditional. While helping conceptualize T3’s breakthrough first product and shaping the brand’s identity, she was simultaneously building a distinguished...

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Axel Turck ist Unternehmer. Aluminiumverarbeitung in Lüdenscheidt, NRW. Als Mittelständler hat er mit all dem zu kämpfen was auch grössere Firmen an den Rand der Verzweiflung oder gar in den Ruin treibt. Im Gespräch mit Frank Wahlig erklärt Turck was ihn manchmal verzweifeln lässt: Energiepreise, politische Unbeweglichkeit, Bürokratie.<br /><br /><br />

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[Philipp Bagus im Gespräch mit Stefan Kooths]<br /><br /> „Marktwirtschaft: Wohlstand, Wachstum, Wettbewerb“ ist der Titel des jüngsten Buches von Prof. Stefan Kooths. In unserer Sendung erörtern wir mit dem Autor, warum die Akzeptanz der Marktwirtschaft so gering ist. Wir diskutieren über Arbeitsteilung und Marktversagen und fragen, ob die Finanzkrise Ausdruck eines marktwirtschaftlichen Versagens ist, warum Preise und Eigentum grundlegend für eine Marktwirtschaft sind und welche Funktionen sie haben.

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<p>When you hear "meal deal" you probably think of fast-food chains, like McDonald’s. But as daily life grows more unaffordable, a new tier of chain restaurants are adopting similar options to hang onto their cash-strapped regulars. It's why Panera just launched a new $10 value meal, and analysts expect other fast-casual joints to follow suit. Plus: Data center construction was up nearly 30% in 2025 but had a limited impact on GDP; buy now, pay later for rent payment comes at a price; we discuss the week’s economic headlines.</p><br/><p>Every story has an economic angle. Want some in y...

<p>a16z general partner Jorge Conde talks with Vasant Narasimhan, CEO of Novartis International, about transforming a 250-year-old conglomerate into a pure play medicines company and unlocking $180 billion of value in the process. They cover Novartis's platform technologies: cell and gene therapies, RNA medicines, and radioligand therapies. They also discuss AI in drug discovery, the rise of China as a biotech competitor, and what Vasant looks for when evaluating startup partnerships, including his advice on the killer experiments and CMC work that can make or break a deal.</p><p> </p><p>Resources: </p><p>Follow Vasant Narasimhan on X...

<p>We create digital breadcrumbs all the time — when we buy something online, when we post on social media, and even when we look up directions on the internet. This is data generally collected by private companies — but how and when should the government be able to access it?</p><br/><p>There have been lawsuits filed recently against the Department of Homeland Security over its collection and use of consumer data. Jeramie Scott, senior counsel and director of the Surveillance Oversight Program at the Electronic Privacy Information Center, explains how the government collects data about us.</p>

<p>This week, OpenAI turns to consultants to get more companies to integrate AI coworkers.</p><br/><p>Plus, Apple will be making its Mac Mini in Texas.</p><br/><p>But first, U.S. Defense Secretary Pete Hegseth met with Anthropic CEO Dario Amodei this week, reportedly asking for unfettered access to the company’s AI model. If not, Hegseth has threatened to cancel a $200 million dollar contract the Pentagon has with the company. This comes after Anthropic's AI model Claude was reportedly used as part of the operation to capture former Venezuelan president Nicolas Maduro.</p><br/><p>An...

<p>Erik Torenberg, Ben Horowitz, and Marc Andreessen discuss how the media landscape has fundamentally changed and what a16z is doing about it. They cover why offense beats defense, why individuals now matter more than corporate brands, why speed wins in the new media landscape, and the difference between oral and written culture on the internet.</p> <p> </p> <p>Resources:</p> <p>Follow Erik Torenberg on X: https://twitter.com/eriktorenberg</p> <p>Follow Ben Horowitz on X: https://twitter.com/bhorowitz</p> <p>Follow Marc Andreessen on X: https://twitter.com/bhorowitz</p> <p><p>Stay Updated:</p...

<p>Send a text</p><p>Nvidia pulls US indices lower but AI rout limited to Wall Street. US and Iran make progress in nuclear talks. But lack of breakthrough keeps gold and oil supported. Pound skids but later steadies after Labour loses UK by-election.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time of publication and may change. Please check our Risk...

In this conversation, Peter discusses significant announcements from Consensus Hong Kong regarding Cardano and the Midnight Network. Key highlights include the integration of Layer Zero for cross-chain interoperability, the introduction of USDCX, a privacy-focused stablecoin, and the upcoming launch of the Midnight Network. The discussion also covers the roadmap for Midnight and the innovative Midnight City project, which aims to showcase the capabilities of the Midnight Network in a fun and engaging way.<br /><br /><br /><br /><b>Takeaways</b><br />Layer Zero integration will enhance Cardano's interoperability.USDCX offers a privacy-focused alternative to USDC.The Midnight Network is set...

<p>We love to hear from our listeners. Send us a message. </p><p>On this week's episode of the Business of Biotech, Brian Hilberdink, President of U.S. Human Pharma at Boehringer Ingelheim, returns to the show during the J.P. Morgan Healthcare Conference, and following his departure from LEO Pharma (see episode 164). Brian talks about new opportunities in obesity, the benefits of private ownership in funding early science, Boehringer's deal strategy, using AI to improve commercialization efforts, and the FDA's selection of zongertinib (in patients with HER2-mutant NSCLC) for the Commissioner's National Priority Voucher program. </p><p>Acc...

<p>On today’s episode, we welcome Tisha Thompson, Founder & CEO of LYS Beauty — the trailblazing clean cosmetics brand proving that high-performance, inclusive, and accessible beauty can coexist. As the first Black-owned clean makeup brand to launch at Sephora, Tisha has quickly built one of the fastest-growing brands in the category, earning major industry awards, viral product moments, and a loyal global following in just five years.<br />Tisha’s journey to founding LYS Beauty was shaped by more than two decades in the beauty industry as a makeup artist, executive, and product developer. From pioneering expansive shade ranges earlier in her...

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<p>On today’s episode, we welcome Brittany Cobb, Founder and CEO of Flea Style and author of the forthcoming book How to Style a Hat — a modern style guide and cultural manifesto centered on confidence, authenticity, and self-expression. What began as a small, underfunded side project rooted in Brittany’s love of flea markets and vintage culture has grown into a nationally recognized experiential retail brand valued at over $15 million, with seven locations redefining how people shop and connect with personal style.<br />Brittany’s path to building Flea Style was shaped by her early career as a lifestyle journali...

<p>We love to hear from our listeners. Send us a message. </p><p>This week's special holiday episode of the Business of Biotech brings seven chief editors from the Life Science Connect family together to talk about the life sciences industry topics, trips, and reporting that mattered most in 2025, and what each editor has planned for 2026. From the RNA, cell, and gene therapy space to small molecule manufacturing, bioprocessing, drug discovery, and outsourcing, the editors weigh in on key industry trends, new developments, and policy surprises from their respective coverage areas. Topics include biotech funding dynamics, FDA leadership, China's...

<p>Send a text</p><p>Investors expect 65bps worth of Fed cuts for 2026. FOMC meeting minutes and Q4 GDP data awaited. Yen recovers some GDP-related losses, aussie and pound slip. Wall Street set to open lower, gold extends pullback.</p><p>Risk Warning: Our services involve a significant risk and can result in the loss of your invested capital. *T&Cs apply.<br/><br/>Please consider our Risk Disclosure: https://www.xm.com/goto/risk/en<br/><br/>Risk warning is correct at the time of publication and may change. Please check our Risk Disclosure for an up to...

This conversation delves into the current state and future of the Cardano ecosystem, focusing on oracles, decentralised applications (DApps), governance, and interoperability. Peter discusses the challenges faced by Cardano's oracle projects, the potential for funding and support for DApps, and the innovative solutions being developed to enhance cross-chain capabilities. The conversation also highlights the Cardano Foundation's efforts to decentralise governance and the significance of security in smart contracts and NFTs.<br /><br /><b>Takeaways</b><br />Charlie 3 is a notable oracle project in Cardano.The Oracle business in Cardano faces significant challenges.Chainlink's integration could have enhanced Cardano's privacy features...

<p>You’re competing with thousands of brands every day—and most brands just get ignored. In this episode, you’ll learn how to create a logo that’s memorable, intentional and consistent so customers notice you now and remember you later when they’re ready to buy. Next Steps:</p> 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us 📚 Learn about the EntreLeadership System™: https://ter.li/system-p 💻 Get EntreLeadership Elite™ for your business: https://ter.li/elite-p ✉️ Sign up to receive tactical tools, advice and resources in your inbox every week: https://ter.li...

<p>a16z's Angela Strange and Gabriel Vasquez speak with Carlos García Ottati, founder and CEO of Kavak, about building Latin America's largest online used car marketplace across Mexico, Brazil, Chile, Argentina, and the Middle East. They discuss why building in emerging markets means constructing four businesses underneath your business, how Kavak replaced copilot tools with AI agents handling 90 to 95% of customer interactions, and what it took to go flat for a year during the transition before growing four times on the other side.</p><p> </p><p> </p> <p><p>Stay Updated:</p><p>Find a16z on You...

<p>Most leaders don’t mess up tough conversations—they avoid them. </p> <p>In this episode, you’ll learn how to face difficult conversations head-on with a clear plan that protects trust, fixes problems faster, and strengthens your team instead of damaging it.</p> <p> </p> <p>Next Steps:</p> <p> </p> <p>· 🎥 Watch the training and use the template to prepare for your next hard conversation: https://ter.li/tiy692</p> <p>· 📞 Have a question for the show? Call 844-944-1070 or send us a message: https://ter.li/ask-us</p> <p>· 📚 Learn about the EntreLeadership System™: https://ter.li/system-p</p> <p>· 💻 Get En...