The Answer to Self-Sabotage in Your Business
<p >Being in business long enough, you've faced this question: "Do I stay the course… or am I self-sabotaging?"</p> <p >In this week's solo episode of The Experienced Entrepreneur, we unravel one of the most complex challenges seasoned business owners face — knowing when something in your business still has staying power, and when your desire to quit is actually coming from fear, fatigue, or avoidance.</p> <p >This is not a beginner conversation. This is a maturity conversation — one that honors both your intuition and your data.</p> <p >For years, the online business world taught us that ease equals...
42 min
2025 December 1
The Best First CNC Machine | Lean Built - Manufacturing Freedom E121
<p>When Jay asks what machine someone should buy to start a small job shop, Andrew gives a direct answer: without committed, repeatable work, he wouldn’t buy anything. But both Jay and Andrew do offer their recommendations, and that opens a broader conversation about the unstable economics of prototypes, customers who send sketches instead of CAD, and why certain jobs are better routed to services like Xometry or Upwork.</p><p><br></p><p>From there, Jay and Andrew compare Haas and Brother machines—control systems, tool changers, rigidity, multi-axis capability, and real reliability differences. Andrew explains why he favo...
Recognizing Your Core Business Identity with Shaina Longstreet
<p >Your brand isn't something you create — it's something you uncover.</p> <p >In this episode of The Experienced Entrepreneur, Marissa Lawton is joined by designer and brand strategist Shaina Longstreet, founder of Dawn and Delight Creative, for a deeply grounded conversation about what it really means to build a business that feels like you.</p> <p >After nearly two decades in creative work, Shaina has developed a powerful philosophy she calls identity-led branding — an approach that starts with who you are at your core, not with trends, templates, or what everyone else is doing online.</p> <p >Together, Marissa and...
Why Profit Margin is My Most Important KPI for 2026
<p >What if the real measure of a healthy business isn't how much you make—but how much you keep?</p> <p >In this episode of The Experienced Entrepreneur, Marissa Lawton shares why she's shifting her focus to profit margin and what that means for seasoned business owners who are ready to step off the "scale at all costs" treadmill.</p> <p >After more than a decade in business, Marissa has seen every iteration of the CEO era—the endless hiring, the tech subscriptions, the outsourcing, the pressure to look like you're growing faster than you actually are. But now, the...
Podcasts
Crypto and Gold in a Multi-Asset Framework
<h2>Episode Highlights:</h2>Why 2025 delivered strong returns across most asset classes — except cryptoBitcoin and Ethereum’s negative YTD performance in contextKey technical breakdowns in Bitcoin using weekly and monthly trend modelsThe erosion of the “digital gold” narrative and rising equity correlationsWhy extreme fear isn’t enough to signal a bottomMacro regime insights: inflation vs. growth sensitivity in BitcoinGold’s resilience and role as a portfolio stabilizerHow Dantes Outlook’s Bitcoin/Gold rotation strategy navigated the year<p>Research & Data Sources:</p>Market and on-chain data from GlassnodeInternal quantitative models from Dantes OutlookAcademic research on asset behavior across macro regimes<p>Happy holida...
Investing Through Global Market Cycles
<h3>Key Topics</h3>The cyclicality of trend, value, momentum, and other stylesWhy Dantes Outlook blends trend, relative strength, and dispersionManaging risk during the crucial mid-30s to 40s accumulation yearsSequence-of-returns risk and why it is the “silent killer” of retirement portfoliosHow rolling return analysis helps investors avoid misleading conclusionsThe case for global diversification beyond U.S.-centric portfoliosWhy non-U.S. equities may be entering a long-term leadership cycleMaintaining a risk mandate you can stick with across market regimes<p>Visit us at www.dantesoutlook.com</p>
Awaken Hope PM Edition with Autumn Canterbury on An Amazing Story of Strength
<p><b>Autumn Canterbury</b> is from Colorado. As a child her parents ran a buffalo ranch and horse ranches. Her father was a horse trainer while her Mother did just about everything horseback. She eventually moved to Albuquerque New Mexico where her parents worked at the racetracks tending the horses. </p> <p>Sadly at 10 years old her mother was killed from a horse accident leaving her in a coma for 6 days and shutting her off life support on the 7th. Her life from there did an ultimate turn. </p> <p>Her father soon met a new woman, having disabled t...
The Con That's Stealing Your Hard Earned Money & The Most Aggressive Attack On Your Future Wealth That No One Is Talking About
<p>Why does stuff feel like its getting more expensive - and why understanding inflation is foundational to growing wealth. </p><p>If you're trying to build real wealth or figure out where to invest in an unpredictable financial system, understanding inflation is critical. This episode breaks down why your hard-earned money buys less every year and why Bitcoin could be your way out of a broken system that quietly robs your future.</p>Discover the truth about inflation and why it's not just prices going up it's your money losing value.Understand how governments dilute your wealth through endless m...
Energy Accounting — The Year-End Audit Successful Entrepreneurs Actually Do
<p >As online business owners head into a new year, most look only at the traditional metrics — revenue, growth, conversions, launches. But seasoned entrepreneurs know those numbers don't tell the full story. The real signals that predict stability, sustainability, and success are often intangible: energy, capacity, creative bandwidth, emotional resilience, and decision fatigue.</p> <p >In this episode of The Experienced Entrepreneur, Marissa breaks down the concept of energy accounting — the year-end audit that mature entrepreneurs use to evaluate the health of their business, not just the output. You'll learn why intangible metrics matter just as much (if not more) than...
Mako Mining – Comprehensive Update At All 4 Projects – San Albino, Moss, Mt Hamilton, and Eagle Mountain
<p>Akiba Leisman, President and CEO of Mako Mining (TSX.V:MKO – OTCQX:MAKOF), joins me for a comprehensive review of all 4 company Projects, on an operational, developmental and exploration perspective. The Company operates the high-grade San Albino gold mine in Nueva Segovia, Nicaragua. Mako owns the Moss Mine in Arizona, an open pit gold mine in northwestern Arizona, which is ramping up production. Mako now controls the permitted Mt. Hamilton Gold-Silver Project located in White Pine County, Nevada, USA as the next key development project in the cue. Mako also holds a 100% interest in the PEA-stage Eagle Mountain Project in...
Magna Mining – Q3 Financials and Operations Review at McCreedy West, Exploration Results and Development Pathway At Levack, and Crean Hill Update
<p>Jason Jessup, CEO and Director of Magna Mining (TSX.V: NICU) (OTCQX: MGMNF), joins us for a Q3 financial and operations review at their producing McCreedy West copper mine, located in Sudbury, Ontario, Canada. We also review the continued high-grade drill results across copper, nickel, platinum, palladium, gold, and silver in more recent assays returned from the ongoing exploration and development work at the Levack Mine. Additionally, we get a nice update on the development pathway at the Crean Hill Project to round out the discussion.</p> <p> </p> <p>Q3 Financial and Operational Highlights:</p> <p> </p> The thr...
Episode 4: A View On Developing Acid Reflux Therapy
<p>Pain in the Gut: Next Generation Therapy for Acid Reflux in the Pipeline</p> <p>In this episode, we are joined by Kjell Anderson, Chief Scientific Officer at Cinclus Pharma, to discuss a novel treatment for acid reflux.</p> <p>Millions of people worldwide grapple with acid reflux, which may progress to gastroesophageal reflux disease (GERD). Chronic acid exposure in the esophagus can lead to discomfort, inflammation, and even erosions—tissue damage that can severely affect a patient’s quality of life. While lifestyle modifications and standard proton pump inhibitors (PPIs) offer relief for some, they are not always effe...
Balancing Global Quality and Value Stocks
<h3>Key Topics Covered</h3>Why major equity indices sit far above trendUnderstanding rotations and style cyclesLessons from past extremes (2021, dot-com bubble, 2008–2021 growth dominance)Why valuations matter for decade-long returnsThe risks behind overspending, AI optimism, and mega-sized corporate debt dealsInsights from the Association for Corporate Growth conference in NYCInnovation vs. investor objectivity: avoiding hope-based investingHow the Dantes Outlook's framework is adjusting factor exposureWhy global value is gaining relative strengthWhy combining value + quality (“QARP”—Quality at a Reasonable Price) smooths returnsQuality as a low-volatility style that resists market drawdownsWhy shifting entirely to deep value today would be a mistakeCreating a global blend ac...
Are You Craving a "Cottage" Business?
<p >What if the next level of success isn't about scaling up — but settling in?</p> <p >In this solo episode, Marissa Lawton explores the idea of right-sizing your business — designing a company that supports your life instead of swallowing it whole.</p> <p >For years, online entrepreneurs have been told that growth is the only direction that matters. More offers, more revenue, more everything. But what happens when "more" starts costing you your peace, your energy, or your joy?</p> <p >Marissa invites you to rethink the "bigger is better" mentality and consider a softer, more sustainable approach — what she ca...
Americas Gold and Silver – Optimization Of The Galena Operations, Acquisition Of The Crescent Silver Mine, The EC120 Mine Ramp Up At Cosalá
<p>Oliver Turner, Executive VP of Corporate Development for Americas Gold and Silver Corporation (TSX: USA) (NYSE American: USAS), joined me for a comprehensive review of the several key optimization initiatives ongoing at their producing 100% owned Galena Complex, located in Idaho, USA; as well as at the EC120 mine at their Cosalá Operations, located in Sinaloa, Mexico. Additionally, we reviewed the news out today regarding the closing of the acquisition of the Crescent Silver Mine located just 9 miles away from their Galena Complex in Idaho.</p> <p> </p> <p>We started off unpacking the multifaceted approach to optimizing their Galena min...
Golden Tickets
<p>Sean Farrington looks at the US Federal Reserve's decision to cut interest rates and what that could mean for the Bank of England.</p><p>We talk to the outgoing boss of GSK on why they're focusing investment in the US over the UK.</p><p>And finally, we look at ticket prices for next year's World Cup.</p>
Inspired by old Portuguese ladies
<p>Who has inspired some of Filipa Fonseca Silva’s best characters? The answer may surprise you. Portuguese author Filipa Fonseca Silva is our latest guest on the podcast and joins Dylan to discuss her books, what she enjoys about living in Portugal, why she is proud of her country and some of her neighbours who have inspired her writing. </p><p><b>FOLLOW OUR GUEST</b></p><b>Filipa's Website</b><b>Filipa on Linkedin</b><p>ABOUT PORTUGAL THE SIMPLE LIFE PODCAST:<br/> "Portugal - The simple life”, an insider's perspective to Portugal.<br/> We already know about Portuga...
Stolen Trailer | Lean Built - Manufacturing Freedom E116
<p>In this episode, Jay recounts the story of a stolen trailer from his tiny home business, leading into a broader discussion on trust, theft, and logistics nightmares. Andrew follows with reflections on manufacturing safety, freight failures, and the unexpected lessons of customer service—both good and bad.</p>
#78 - AI Agents Unleashed Virtuals Autonomous Trading and the Crypto Agentic Economy
Dive deep into the agentic economy, where <b>AI Agents</b> and <b>Virtuals</b> are transforming decentralized finance. Learn how sophisticated <b>Crypto AI</b> is moving beyond simple bots to enable truly <b>autonomous trading</b> strategies. We explore the infrastructure powering this revolution—from smart contracts to decentralized compute—and discuss the massive investment potential. Understand the shift from passive holding to active, automated, and intelligent participation in the market. Is your wallet ready for the future of finance run by autonomous AI?<br /><br />This episode includes AI-generated content.
Episode 7: A View On Spray-Drying mRNA-based Therapies
<p>A View On Spray-Drying mRNA-based Products </p> <p>Delivering mNRA Therapies: A Bullseye for Asthma and Future Pandemics<br> In this episode, we speak with Carsten Rudolph, CEO and co-founder of Ethris, about a novel spray-dried mRNA therapy designed to restore immune balance in asthma patients and prepare for future pandemics.</p> <p>This episode of A View On takes us deep into the lungs, where science, engineering, and medicine converge. Our guest, Carsten Rudolph, CEO and co-founder of Ethris, explains how his team is developing inhalable mRNA-based therapies for chronic respiratory conditions like asthma, rare diseases such as...
Chilling out in Portugal
<p>Why is Portugal the perfect place to ‘chill out’? Our latest guest, Marieka Finot is a financial literacy expert and helps people ‘chill out’ about their finances. Born in France and having lived in London for 10 years she is well versed in a busy life and now finds her balance and rest in Portugal. She chats to Dylan about how her life has changed since she discovered Portugal’s quality of life, how Portugal is a lovely family destination and how work-life balance is a daily and natural way of life in Portugal. </p><p><b>FOLLOW OUR GUEST</b></p><b>Ma...
The Power of Fractional Expertise | Lean Built - Manufacturing Freedom E117
<p>Andrew and Jay dive into the art of optimization, from shaving seconds off CNC cycles to teaching kids the power of one-piece flow. Andrew shares how tuning a Brother machine saved 13 hours across a 5,000-part run and reflects on when optimization really pays off. The two discuss lean principles in action, shop tours, and the balance between efficiency and creativity before discussing the value of fractional expertise. From hiring a CPA who acts like a dashboard of financial sensors to bringing in part-time specialists who reveal blind spots and move the needle in tens of thousands, they show how...
Sunday Church Services with Prince of Peace Lutheran Church 12_14_25
<p><b>Sunday Church Services with Prince of Peace Lutheran Church</b></p> <p>Airdate: 12/14/25</p> <p><b>Come Worship With Us!</b></p> <p>Prince of Peace Lutheran Church</p> <p>Pastor: Kevin Martin </p> <p>10250 Haynes Bridge Road</p> <p>John's Creek Georgia 30022</p> <p>Phone number 770-475-4250</p> <p>Church Website: http://poplutheranchurch.com</p> <p>Email: Office@poplutheranchurch.com</p>
#70 - Blockchain in Insurance Practical Use Cases for Health, Auto & Supply-Chain
Let’s dive into the concrete use cases of blockchain within insurance: how it is being used in health for secure records and wearables, in auto for usage-based insurance and real-time claims, and in supply-chain connected policies where provenance and authenticity matter. We’ll feature examples, highlight the benefits of transparency and cost-reduction, and cover the roadblocks to implementation.<br /><br />This episode includes AI-generated content.
Episode 1: A View On Emerging Trends in Pharmaceutical Manufacturing, live from CPHI Milan
<p>We are back! Discover the latest in pharmaceutical innovation from CPHI Milan with A View On! This episode explores advancements in bioconjugates, AI-driven drug development, targeted capsule delivery, and new solutions in cell and gene therapy that are transforming patient care. Tune in to hear from Lonza experts on the future of pharma and biotech.</p>
Books, shelves & elves
<p>Felicity Hannah hears from the boss of Waterstones and gets an update from Tunbridge Wells.</p><p>Elsewhere, the reviews website Trustpilot's share price has PLUNGED by almost 30%, wiping more than £200 million pounds from its value. We ask what's happening to the FTSE 250-listed firm.</p><p>And it's the Christmas tradition that's become a global multi-million-dollar franchise - Fliss speaks to one of the founders of the company behind The Elf on the Shelf.</p>
Cash In The Bank Is NOT YOURS + Cash Is Keeping You Poor (And How Millennials Are Using Bitcoin To Protect Wealth)
<p>If you can’t feel your physical money anymore, is it still real?</p><p>Whether you're slipping crisp £20 notes into birthday cards or reminiscing about jam jars full of coins, today’s money doesn’t feel like it used to because it isn’t. In this warm and witty call with Mildred, a retired listener with old-school values, we unpack why <b>cash has vanished</b>, how <b>digital finance</b> quietly changed everything, and why <b>Bitcoin</b> might be the first truly real money in decades.</p>Understand why the money in your bank isn’t really your...
Cocoa Hops
<p>Sean Farrington discusses the rising bills that could hit the pub sector, in the wake of business rates changes. </p><p>Elsewhere, he'll turn his attention to the US, where the Fed will announce its decision on rates.</p><p>And, will consumer demand keep up with increasing chocolate prices?</p>
Hustle Mode vs Sprint Energy
<p >There's a difference between running a business and playing at one.</p> <p >In this episode of The Experienced Entrepreneur, Marissa Lawton breaks down what it really means to work hard without burning out — and how to reclaim your energy through intentional effort.</p> <p >You'll learn how to spot the difference between hustle (reactive, fear-based, endless) and a sprint (focused, strategic, time-bound). Marissa shares her framework for designing "seasons of sprint" that move your business forward without tipping you into exhaustion — including how to track what's working, when to rest, and how to tell if you're running your busi...
Running Your Shop at 100% Capacity Is a Mistake | Lean Built - Manufacturing Freedom E125
<p>Jay and Andrew discuss real-world shop challenges like air quality, ventilation, coolant selection, and bandsaw blade performance. The conversation expands into capacity planning, why running at 100% utilization is a hidden liability, and how maintaining margin and flexibility allows shops to respond quickly when customers need help.</p><p><br></p><p>Along the way, they touch on safety systems that fail when alerts are too distant from the problem, lessons from catastrophic industrial accidents, and why local, thoughtful gestures like good donuts or quality coffee build stronger vendor and customer relationships than generic (or just plain bad) corporate gifts.<...
Going hostile
<p>Sean Farrington looks at Paramount's $108bn hostile bid, as the battle for Warner Brothers continues to heat up.</p><p>Elsewhere, he'll be discussing a bill on railways that returns to Parliament today which could see passengers buying tickets directly from the government.</p><p>And, he'll take a look at some new data that shows just how much money shoppers have been spending in the last month.</p>
Episode 8: A View On Process Analytical Technologies
<p>Process Analytical Technologies: Real-Time Insight for Smarter Manufacturing</p> <p>In this episode, we speak with Carrie Mason, Thad Webster, and Ryan McDougall from Lonza’s PAT Center of Excellence about how Process Analytical Technologies are transforming the way biologics are developed and produced.</p> <p>This episode of A View On takes us inside the manufacturing suite, where data, sensors, and decision-making converge in real time. Our guests explain how process analytical technologies (PAT) bring advanced analytics and spectroscopy directly into bioprocesses, allowing operators and scientists to “see” what’s happening inside a bioreactor without taking samples out.</p> <p>Tr...
3 Tax Mistakes Bitcoiners Make That Can Erase Years of Gains - Interview With The Bitcoin Accountant
<p><b>What are you </b><b>really</b><b> going to do when it's finally time to sell your Bitcoin and then pay your tax bill? </b></p><p>If you're investing in Bitcoin, the exit plan is just as critical as the entry point but most people have no clue what selling actually looks like, especially with looming capital gains taxes, evolving lending options, and future regulations.</p><p>I speak to Robin Thatcher - The Bitcoin Accountant to learn more about bitcoin and tax. Click above to go to his website. </p><p>In this episode, you’ll u...
Positive Talk with Kevin McDonald and Ciara Lewis
<p>Positive Talk with Kevin McDonald and Ciara Lewis</p>
Gina Gardiner & Friends and Kerry Benjamin
<p><b>KERRY’S STORY</b></p> <p>From battling eczema to building StackedSkincare.</p> <p>Since childhood, I battled severe <b>eczema</b>, a relentless struggle that began when I was just five years old. By eight, it had spread to my eyes and lips, leaving me feeling isolated and insecure.</p> <p>While many children grow out of eczema, mine only worsened. I endured monthly steroid shots, sleepless nights with ice packs, and even medication to stop the scratching.</p> <p>In 2008, my skin struggles reached a breaking point. I woke with excruciating elbow pain that turned out to...
My Home in Portugal - Vic
<p>On this edition of 'My Home in Portugal’, Dylan is joined by Vic Dee, originally from Belgium, Vic bought an investment property right here on The Silver Coast. He shares how after coming back and forth to Silver Coast, it felt even more like home . We recorded this episode from Vic’s beautiful home and this is some of his story…</p><p><b>ABOUT PORTUGAL THE SIMPLE LIFE PODCAST:<br/> <br/></b>"Portugal - The simple life”, an insider's perspective to Portugal.<br/> We already know about Portugal’s fantastic weather, food and people. In this podcast, we go deeper to...
Positive Talk with Kevin McDonald and Wendy Babcock
<p>Positive Talk with Kevin McDonald and Wendy Babcock</p>
Why Even a London Pick Pocketer Converts To Bitcoin Because Of Its Growth Potential
<p>Think Bitcoin is a waste of money because it doesn’t pay dividends or generate income?</p><p>Many people dismiss Bitcoin as an unproductive asset especially if they’re focused on fast cash or traditional investments like stocks, property, or finance-backed portfolios. But here’s the truth: Bitcoin may not pay you income, but it can build serious wealth. In this episode, we break down what makes Bitcoin a game-changing tool for long-term financial freedom, especially for those who’ve never invested before.</p>Learn how investing in Bitcoin during the pandemic could’ve turned £10,000 into over £215,000 without needing stoc...
Flu season
<p>Felicity Hannah hears how businesses can respond to staff calling in sick during the flu outbreak, and why some pharmacies are experiencing a shortage of vaccines. And, with just ten days left until Christmas, the director of a shopping centre tells us whether Gen Z is driving a resurgence of the in-person retail experience.</p>
Banyan Gold - AurMac Drilling Update: Extending High-Grade Mineralization Within and Outside Of The 7.7Moz Resource
<p>In this KE Report company update, I am joined by Tara Christie, President & CEO of Banyan Gold (TSX.V:BYN - OTCQB:BYAGF), to recap recent drill results from the AurMac Project in the Yukon. The focus is on how drilling this year is successfully defining and expanding higher-grade gold zones within one of Canada’s largest undeveloped gold resources.</p> <p>Key discussion points include:</p> High-Grade Gold Definition: Drill results confirming +1.0 g/t gold zones at the Powerline and Airstrip deposits.<br> <br> Resource & Pit Expansion: Step-out drilling converting waste to mineralization and extending conceptual pit limits.<br...
Building a Company That Can Survive Without You | Lean Built - Manufacturing Freedom E122
<p>Andrew opens with a simple shop-floor idea that changed how their teams celebrate progress: a six-inch clear tube filled with colored marbles. That playful visual turns into a deeper conversation between Jay and Andrew about the power of collective improvement, the limits of mental capacity as organizations grow, and the art of estimating through Fermi numbers. They move from marbles to antennas, from CNC stencils to parabolic reflectors, and from daily shop habits to long-term business planning.</p><p>The episode also takes a serious turn as they take a blunt look at succession planning, wills, and preparing your...
Positive Talk with Kevin McDonald and Michael Stone
<p>Positive Talk with Kevin McDonald and Michael Stone</p>
Is Portuguese difficult?
<p>Is Portuguese a difficult language? This week's guest helps us answer that question. Catarina Bento is the founder of The Bento Atelier, where she helps people learn European Portuguese and ‘say it like a local’. She chats with Dylan about some of the nuances of the Portuguese language, tests Dylan’s Portuguese and talks about how your experience of our amazing country can be so much richer when you understand and can enjoy conversations in Portuguese. </p><p><b>FOLLOW OUR GUEST:</b></p><b>Catarina’s website</b><b>Catarina on Instagram</b><p><b>ABOUT PORTUGAL THE SIMPLE LI...
Cloudy with a chance of growth?
<p>Sean Farrington hears why the Organisation for Economic Cooperation and Development has upgraded UK growth but warns Rachel Reeves that higher taxes and tight spending plans risk squeezing households and slowing the recovery - with unemployment rising. </p><p>And Ofsted have released their first AI report, which says classroom tech is barely improving results, yet teachers fear pupils who don’t learn AI tools could lose out in the jobs market - Sean looks at the details.</p>
Brien Lundin & Jeff Christian - Silver’s $60+ Surge & The “Debasement Trade” Playbook
<p>This Weekend Show is all about precious metals momentum, and the why behind it. Brien Lundin argues we’re watching the classic bull-market baton pass (silver + miners leading gold), while Jeff Christian breaks down what the data actually shows behind silver’s explosive run above $60, and why volatility could cut both ways in the weeks ahead.</p> Segment 1 & 2 - Brien Lundin, editor of Gold Newsletter and host of the New Orleans Investment Conference, joins the KE Report Weekend Show to break down his massive year-end issue - covering macro trends, metals and market outlooks, dozens of junior mining updates, and...
Episode 5: A View On Smart Capsule Technology
<p>A Swallow Instead of a Jab? A Capsule That Delivers Like an Injection</p> <p>In this episode, we’re joined by Karsten Lindhardt, Founder and CEO of Biograil, to explore how a spring-loaded oral capsule could revolutionize drug delivery—offering patients a needle-free alternative with the same therapeutic impact as subcutaneous injections.</p> <p>From insulin to monoclonal antibodies, biologic drugs are typically delivered through injections—often multiple times a week. For many patients, this isn’t just painful; it disrupts daily life and can be a major barrier to long-term treatment compliance. Imagine a world where those same treat...
Episode 6: A View On Improving Microbial Manufacturing
<p>Unlocking Microbial Manufacturing: Innovation Across the Pipeline <br /></p> <p>For more than 40 years, microbial fermentation has been the workhorse of biologic manufacturing. From the first recombinant insulin to today’s increasingly complex therapeutic formats, the technology has consistently adapted to meet the needs of patients, developers, and regulators. </p> <p>Karlheinz Flicker, Director of Microbial R&D, offers a strategic perspective on how microbial systems like E. coli and Pichia pastoris support emerging non-Fc biologics such as nanobodies and cytokines. Later, Joan Cortada, Associate Principal Scientist, walks us through a promising innovation in protein refolding that uses high pressure to...
Episode 2: A View On Antibody-Based Therapies
<p>Antibody-Based Therapies: Transforming Modern Medicine</p> <p>In this episode, we are joined by Ronnie Wei, Head of Biologics Discovery and Development at ModeX Therapeutics, and Atul Mohindra, Head of R&D for Biologics at Lonza, to explore the development and manufacturing of monoclonal, bi-, and multi-specific antibodies and their transformative role in modern medicine.</p> <p>Everyday life is filled with stories of medical breakthroughs—new cancer treatments, therapies for rare diseases, and vaccines that protect millions. At the heart of many of these advances are antibody-based therapies. These life-changing medicines leverage the natural defense systems of the bo...
Majoring On The Majors | Lean Built - Manufacturing Freedom E124
<p>Tiny improvements won’t move the company forward unless leaders also make the big decisions. Lean is life-changing, but you can’t lean your way into a clear vision. You have to choose it. That means looking honestly at customers, pricing, equipment, automation, space, and your team, and fixing what really bugs you at the highest level. That lesson is at the crux of this jam-packed episode which also covers: visual controls that save mental energy, smarter checklists that stop cultural drift, and a simple light-curtain jig that turns a tedious sewing task into an effortless one.</p>
Arizona Sonoran Copper – Key Metrics From The Cactus Project PFS, Envisioned Mine Plan, Exploration Update, Permitting, Capital Raise, Pathway To Development
<p>George Ogilvie, President and CEO of Arizona Sonoran Copper (TSX:ASCU – OTCQX:ASCUF), joins us to outline the key metrics from the Pre-Feasibility Study (PFS) on the Cactus Project in Arizona and the envisioned mine plan. We also get an exploration update, more clarity around the permitting process, discuss the recent capital raise, and review the pathway to production.</p> <p> </p> <p>PFS Highlights include:</p> Simple open pit / SXEW operation producing approximately 103,000 tonnes (226 million lbs) of estimated average annual copper cathodes over the first 10 years of mining, which would make Cactus the third largest cathode producer in the...
A View On Innovating Drug Development and Manufacturing
<p>Innovating Drug Development and Manufacturing: How External Collaborations Shape the Future of Biotherapeutics</p> <p>In this episode of A View On, we speak with Andrew Brown, R&D Director at Lonza’s Integrated Biologics, and Zara Asgharpour, Director of External Innovation in Integrated Biologics, about how evolving molecular formats and external innovation are transforming the way biotherapeutics are developed and manufactured.</p> <p>The world of biotherapeutics is in constant evolution, with new molecular formats, scientific insights, and strategic partnerships shaping the medicines of tomorrow. These increasingly complex biologics require new approaches in development and manufacturing, from developing adv...
AbraSilver Resource – Drill Hole Testing Porphyry Potential at Oculto East Intercepts Broad Mineralization Of 274 Metres Grading 0.60 g/t Gold
<p>John Miniotis, President and CEO of AbraSilver Resource Corp (TSX: ABRA) (OTCQX: ABBRF), joins us to review the latest batch of drill assays announced December 10th, returning the broadest gold mineralization intercepted to date, from the ongoing Phase V exploration program. These holes were testing for the potential of porphyry mineralization at dept at the Oculto East area of their wholly-owned Diablillos property in Salta Province, Argentina. </p> <p> </p> <p>John reviews the three latest drill holes from the ongoing Phase V exploration program and that hole # DDH 25-085 at Oculto East intersected a broad 274.0 metre ("m") interval grad...
Wake Up to Cricket
<p>Sean Farrington hears about the business of cricket as the 2nd Ashes Test match commences. We speak to a business owner in Tunbridge Wells as water outages persist for thousands of properties. And what does the future hold for Britain's Nuclear industry? We find out.</p>
Think in Seasons, Not Sprints | Lean Built - Manufacturing Freedom E118
<p>How do you lead your company through the chaos and cadence of a production year without burning out your team or yourself? In this episode, Jay and Andrew unpack Andrew’s “Four Quarter Business Rhythm” document, his framework for understanding seasonal production cycles, planning proactively, and preparing his team to thrive when it's go-time. From practical PTO policies to government fiscal-year quirks, from proactive inventory planning to Lean Day Trello boards, from baseball stats to busted CNC foot pedals, this episode is packed with leadership lessons, hard-earned shop wisdom, and actionable strategy.</p>
Portfolio Update: Emerging Market Regional Tilts Drive Outperformance
<p>Topics Covered:</p>November performance recap for the Moderate Global Balanced PortfolioActive equity selection and regional tiltsFixed income positioning: intermediate-term U.S. TreasuriesYTD performance vs. benchmark and risk-adjusted resultsBitcoin–Gold Rotation strategy: why gold dominated signals this yearHow aggressive clients can use the rotation sleeveNew absolute-return breakout strategy and its early outperformanceHow global diversification and trend-based discipline helped narrow tracking errorWhere to find the full allocation breakdown (Substack)<p>Key Highlights:</p>Portfolio outperformed the global 60/40 benchmark by 30 bps in NovemberEquity sleeve remains 63% of the portfolio, with strong regional contributionsFixed income tilts added to monthly returnsBitcoin–Gold model returned 41% YTD...
How to Sell in Today's Market
<p >The online business space has changed — and so has the way people buy.</p> <p >In this episode of The Experienced Entrepreneur, Marissa Lawton breaks down what's really happening behind today's slower sales cycles and why it's not a bad thing. You'll learn how buyer psychology has evolved, what the new customer journey looks like, and how to adapt your business strategy with more steadiness, connection, and confidence.</p> <p >Marissa shares how the old "seven touchpoints before a sale" rule has ballooned to nearly eighty — and what that means for your marketing, your mindset, and your metrics. You'll expl...
I want to be Portuguese when I grow up
<p>Have you ever met a ‘nata-holic’? Alexa is addicted to Pasteis da Nata, the famous Portuguese pastry. Alexa is originally from Poland but loves Portugal, so much so that she wants to Portuguese when she ‘grows up’. She is our latest guest on the podcast and in a humorous episode Alexa chats to Dylan about, amongst other things, how she discovered Portugal by accident, why she loves this country so much, the art of the long goodbye, how Portugal has changed her face and what it would take for her to become Portuguese…</p><p><b>FOLLOW OUR GUEST</b></p><b>A...
Scottie Resources – Trial Mining Bulk Sample Will Generate CAD$9M, Update On Ore Sorting, Feasibility Study Workstreams, Exploration Program, and DSO Pathway
<p>Dr. Thomas Mumford, President of Scottie Resources (TSX.V:SCOT – OTCQB:SCTSF), joins me to review the key takeaways from the Bulk Sample report, when compared with expectations from the October 2025 Preliminary Economic Assessment (PEA). Additionally, we get an update on the ongoing ore-sorting studies, what was learned from this year’s drill program, the preparation for the largest drill program to date in 2026, and the Feasibility Study workstreams underway at the Scottie Gold Mine Project; located in the Golden Triangle of British Columbia.</p> <p> </p> <p>The recent PEA outlined a robust Direct-Ship Ore (“DSO”) development scenario for the Scot...
The Ordinary Business Revolution - with Jessica Freeman
<p >What if "ordinary" isn't a limitation — but the new definition of success?</p> <p >In this conversation, Marissa Lawton and longtime entrepreneur Jessica Freeman — founder of Jess Creatives and The Ordinary Business — explore what it really means to build a business that's sustainable, satisfying, and still fully your own.</p> <p >Together, they unpack how the online business world has evolved over the last decade — from the hustle-heavy, seven-figure dreams of the 2010s to a quieter, more grounded version of success that prioritizes freedom, fulfillment, and a well-lived life.</p> <p >Jessica shares how her Ordinary Business philosophy was born fro...
Invest in Crypto or Bitcoin? What You Need to Know Before Growing Your Wealth (And Losing Your Money)
<p>Still think Bitcoin and crypto are the same thing? That mindset might be costing you real long-term wealth.</p><p>If you're confused by the sea of altcoins and marketing hype in the crypto space, you're not alone. In this episode, Myles teams up with Bitcoin expert Robin Seyr who’s interviewed over 700 thought leaders to explain why Bitcoin is fundamentally different from everything else labeled “crypto.” You’ll finally understand the difference between protocol and product, security vs. speculation, and why this distinction matters for your financial future.</p>Learn why Bitcoin’s decentralized, secure protocol makes it the only d...
Portfolio Update: Positioning for Global Opportunities
<p>In this episode:</p>Why extreme bearish sentiment often precedes market recoveriesThe role of relative strength in identifying global equity opportunitiesHow Dantes Outlook is adapting its allocation framework amid shifting leadershipThe importance of staying systematic and globally diversified through volatility<p>For full portfolio updates and performance insights:<br />👉 Access the Alpha Capture Portfolio Report on Dantes Outlook Substack (subscribers only)</p><p>Disclaimer:<br />This podcast is for informational purposes only and does not constitute investment advice. Dantes Outlook LLC is a registered investment advisor. Past performance is not indicative of future results. Investment decisions can change based on...
You’re NOT Too Late to Bitcoin. With Robin Seyer. Why That Thinking is Financial Self-Sabotage.
<p>Have you ever thought, “I missed the boat on Bitcoin”? This episode will prove you wrong and show you why that belief could cost you more than you realise. </p><p>I speak with Robin Seyer to understand why we are not late to bitcoin. Robin is the host of his own podcast on bitcoin and has interviewed over 700 people in bitcoin. </p><p>If you're a millennial wondering whether Bitcoin still has room to grow or if it’s too late to invest, this episode breaks down why that hesitation may be holding you back from long-term wealth creation...
Wild wild Portugal
<p>For our final episode of Season 3, Dylan is joined by Barbara Veiga. Born in Brazil, Barbara is a public speaker, visual artist and environmental activist focused on climate action with an emphasis on oceanic life. She dedicated more than seven full, consecutive years of her life to traveling the seas around more than 90 countries and haswritten about these experiences in her memoir “Seven Years in Seven Seas” (Sete Anos em Sete Mares). After her seven years of sailing the world, Portugal was the place she wanted to call home where she has been ever since. She chats to Dylan abou...
Balancing Stocks, Bonds, and Metals
<p>In This Episode:</p>Why Treasuries are having their strongest October in years.The significance of the negative stock–bond correlation and what it signals for portfolios.Inflation and labor market trends supporting potential Fed rate cuts.How gold, palladium, and other metals fit into a late-cycle allocation.Our portfolio adjustments: longer-duration Treasuries, selective pro-cyclical tilts, and risk management strategies.Why loose financial conditions continue to support speculation — and how we’re positioning for the next phase of the cycle.<p>Resources & Links:</p><p>Subscribe to our Dantes Outlook Substack for full market intelligence updates and model portfolio insigh...
Q3 2025 Global Market Intelligence
<p>In this episode:</p><p>Key findings from the Q3 2025 Market Intelligence Report</p><p>Why asset dispersion is narrowing and what that means for diversification</p><p>Where our models see strength—select metals, emerging markets, and duration</p><p>The implications of a neutral dollar and extended U.S. equities</p><p>How we’re positioning portfolios for selective exposure and flexibility</p><p>Referenced in this episode:</p><p>Dantes Outlook Market Intelligence Report (Q3 2025)</p><p>Substack: https://dantesoutlook.substack.com</p><p>Learn more: https://dantesoutlook.com</p><p> </p>
Middle East Investment Takeaways, Riyadh & Dubai
<p>Topics Covered:</p><p>– Introduction: A new perspective from Riyadh and Dubai</p><p>– First impressions of the Middle East’s financial centers</p><p>– Inside the CMT Global Investment Summit: sentiment, structure, and surprises</p><p>– Regional vs. U.S. focus: where investors see opportunity</p><p>– The Dantes Outlook framework: mapping the market and business cycles</p><p>– Challenging assumptions about the Middle East’s global role</p><p>– Key insights investors should be watching</p><p>Visit us at DantesOutlook.com</p><p> </p>
Awaken Hope with Dr. Brad Montagne on Chronic illness
<p>Dr Brad is a passionate caregiver with a deep tool chest of decades of research, studies, and clinical application of Functional Medicine in restoring health to those with chronic illness. It is common for him to be able to give people their life back that no other caregivers have been able to help.</p> <p>His compassionate understanding comes from years of his own struggles with chronic illness, and the Lord giving him the tools to help himself and others get free from the prison of ongoing sickness.</p> <p>He has been there, he cares, and he walks...
Saudi Market Leadership & Global Cycles
Abdulelah’s background and pathway to technical analysisMentorship, the CMT Association, and Riyadh chapter goalsGrowth opportunities in Saudi Arabia and the UAECyclicality, sector exposure, and local vs. global dynamicsUsing relative strength and market breadth in regional analysisAdjusting time frames and macro considerationsVision for growing a regional professional networkLooking ahead to the CMT conferences in Riyadh and Dubai<p>Visit us at www.dantesoutlook.com</p><p>Email damanick@dantesoutlook to request a meeting.</p>
Heliostar Metals - Cerro del Gallo PFS, Building Toward 300,000 oz/year
<p>In this company update, I’m joined by Stephen Soock, VP Investor Relations & Development at Heliostar Metals (TSX-V:HSTR - OTCQX:HSTXF - FSE:R0G1), to discuss the newly released Pre-Feasibility Study (PFS) on the Cerro del Gallo Project and how it fits into the company’s broader production pipeline.</p> <p>Key discussion points include:</p> Cerro del Gallo PFS Economics<br> Profitable base case at $2,300 gold with strong leverage to higher gold prices and a long-life open-pit, heap-leach operation.<br> <br> Resource & Production Upside<br> Only a portion of the total resource is included in reserves, leav...
Should You Even Make a Business Plan for 2026?
<p >Should We Be Planning 2026? (How to Lead Your Business in an Unpredictable Market)</p> <p >If you've been wondering whether it even makes sense to plan for 2026 with the market shifting under our feet — this episode is going to feel like a deep exhale.</p> <p >In today's solo episode, we're talking about what mature entrepreneurs already know:<br /> Annual planning isn't about predicting the year. It's about directing it.<br /> It's about creating a structure sturdy enough to hold you, even when the market doesn't cooperate.</p> <p >I'm walking you through the exact framework I use — the Rock...
Positive Talk with Kevin McDonald with Ben Stein
<p>Positive Talk with Kevin McDonald with Ben Stein</p>
#76 - Crypto Market 2025 Ethereum Upgrades, Bitcoin Trends & Blockchain Technology
Unlock the future of cryptocurrency as we dissect Ethereum's ambitious roadmap and its impact on the broader digital asset ecosystem. Explore how the Pectra and Fusaka upgrades are revolutionizing blockchain scalability with 10x data capacity increases, why Layer-2 networks are crushing transaction costs by 90-98%, and how post-quantum cryptography is securing the future of decentralized finance. Understand the macroeconomic forces driving Bitcoin and altcoin prices, the institutional adoption wave transforming crypto from speculation to sustainable integration, and breakthrough innovations in Verkle Trees reducing proof sizes by 75%. From rollup economics to stablecoin supremacy, AI-powered DeFi protocols to tokenized real-world assets, discover...
#73 - Bitcoin ETF Options: Revolutionizing Institutional Crypto Risk
This episode delves into the groundbreaking launch of options on Bitcoin spot ETFs, especially on BlackRock’s iShares Bitcoin Trust (IBIT). We explore how $1.9B in notional volume on day one represents a watershed moment for institutional crypto adoption, risk hedging, and speculation. What does this mean for market liquidity, regulatory dynamics, and the future of regulated crypto exposure? Get a full breakdown of how these derivatives could reshape the financial landscape.<br /><br />This episode includes AI-generated content.
#71 - Ethereum Killers, Solana Killers & Next-Gen Chains
Welcome to the heart of Web3 rivalry, where communities rally behind “Ethereum killers” and “Solana killers” betting on the next-gen chains. This episode dissects what gives these challenger blockchains their edge — whether it’s novel consensus models, ultra-fast TPS, or radical decentralisation. We look at ecosystem narratives, capital inflows, and the real-world adoption that could tip the balance. Plus, we unpack whether these titles are hype or hard reality for investors and devs alike.<br /><br />This episode includes AI-generated content.
Why £ $ & € Will Destroy Your Wealth and Make You A Debt Slave (And How Bitcoin Is The REAL way to become wealthy)
<p>Is Bitcoin really chaotic, or is it the most perfectly ordered form of <b>money</b> ever created?</p><p>If you’ve been taught to believe that <b>Bitcoin</b> is risky, confusing, or even anarchic, this episode will challenge everything you thought you knew. Whether you're from a culture of financial discipline or just starting your <b>investing</b> journey, this Mythbuster-style conversation shines a light on the real reason Bitcoin was created not to destroy financial systems, but to bring lasting <b>order</b> to them.</p>Learn why Bitcoin’s fixed rules offer more financial <b>sta...
Lessons from the Gemba Summit in Belfast | Lean Built - Manufacturing Freedom E119
<p>Fresh off the Gemba Summit in Belfast, Andrew shares lessons from across the pond with Jay. What starts as a deep dive into lean culture at the Titanic Belfast turns into a candid conversation about scaling small businesses, visiting your vendors, and rethinking what it means to “fix what bugs you.”</p><p><br></p><p>Andrew and Jay unpack how lean principles evolve when your company outgrows the two-second mindset. Andrews tells about conversations with Toyota UK’s Alan Weir, British Rototherm’s Oliver Conger, and Tom Hughes of GembaDocs. They also discuss the practical takeaways from Greg Crabtree...
Portugal is the tortoise...
<p>Is Portugal the tortoise or the rabbit? Our latest explains why he thinks Portugal is the tortoise. Thomas Stark is a dad, a husband, a triathlete and a business man. Originally from Germany, Thomas is passionate about Portugal and his company supports forward-thinking companies to start and scale in Portugal. He chats to Dylan about why he loves Portugal, how Portugal has perfected work-life balance, how Portugal has so much potential but has kept it’s simplicity, authenticity and quality of life. </p><p><b>FOLLOW OUR GUEST</b></p><b>Stark & Partners Website</b><b>Thomas on Linkedin</b><...
Cyclical Rotation from High Beta to Quality Stocks
<p>Topics Covered:</p>High-beta vs. low-volatility stock performanceWhy narrow market breadth can lead to leadership shiftsSigns of improving fundamentals after a mild earnings recessionThe impact of new small-business tax cuts on growth and jobsThe case for quality stocks in a late-cycle environmentGlobal opportunities in value and emerging-market equities<p>Key Takeaway:<br />Rotation and selectivity — not just momentum — will shape the next leg of this market.</p><p>Visit us at dantesoutlook.com</p>
My Home in Portugal - Ron & Mike
<p>On this edition of 'My Home in Portugal’, Dylan is joined by Ron & Mike, a couple from the USA who bought an investment property right here on the Silver Coast after promising each other on the plane to Portugal that they would not be buying anything. We recorded this episode from Ron & Mike’s beautiful new home and this is some of their story…</p><p><b>ABOUT PORTUGAL THE SIMPLE LIFE PODCAST:<br/> <br/></b>"Portugal - The simple life”, an insider's perspective to Portugal.<br/>We already know about Portugal’s fantastic weather, food and people. In this podcas...
Melting Point
<p>Felicity Hannah speaks to the CEO of the Magnum Ice Cream Company as it finishes its first week as a listed company. Plus, what does the latest Knives Out tell us about Hollywood?</p>
How To Not FIGHT With Your Family This Christmas Season - Especially When Talking About Bitcoin, Wealth and Money - Xmas Special
<p>Ever been mocked at the dinner table for investing in Bitcoin - especially when prices are down? Or just want to discuss this new thing you are learning about called bitcoin, but dont want to blow up the holiday vibes. </p><p>I bring my wife Becs, a Professional Workplace Mediator and Conflict Coach on to discuss how to manage tricky chat this holiday seson. </p><p>With the holidays around the corner, many families are gearing up not just for turkey, but tension, especially when topics like money, politics, and Bitcoin come up. If you're passionate about Bitcoin an...
Portugal is not its airports
<p>When your first experience of Portugal is its airport, this may not be the best of starts. Andrew Bryant talks about this and more as our latest guest on the podcast. Andrew is a best-selling author, keynote speaker and podcast host who loves getting out of the airport and experiencing the real Portugal. He chats to Dylan about, amongst other things, his first experiences of Portugal, what he misses about Portugal when he travels and what he loves about coming back. </p><p><b>FOLLOW OUR GUEST</b></p><b>Andrew’s website</b><p><b>ABOUT PORTUGAL THE SIM...
Bitcoin’s Crashing?! Get EXCITED. Why That’s Your Golden Opportunity To Build Generational Wealth
<p>What if everything you’ve heard about Bitcoin crashing was missing the real opportunity behind the panic?</p><p>If you're unsure about investing in Bitcoin because of its volatility or the fear of it crashing, you're not alone. This episode breaks down the true meaning behind a "crash" and explains why understanding the difference between a drawdown and total collapse could be the key to securing your financial future even when the headlines scream doom.</p>Learn the historical pattern of Bitcoin crashes and why it has always bounced back stronger.Discover why seasoned Bitcoiners actually get excited du...
Office for Bodged Responsibility
<p>Sean Farrington explores why Richard Hughes has quit as head of the OBR after a Budget-day publishing blunder, and what it means for trust in the watchdog’s forecasts.</p><p>Trainees at an accountancy firm will be sent on secondments at bars, pubs and restaurants to help develop their 'front of house' skills - Sean finds out why. </p><p>And it's Christmas advert season; can local shops compete with the big brands? Small businesses in Hexham, in Northumberland, have banded together to have a go by creating their own Christmas Ad.</p>
Episode 11: A View On the History of Capsule Manufacturing
<p>Tracing the Evolution and Future of Capsule Manufacturing </p> <p>In this episode, we are joined by Ljiljana Palangetic, Associate Director of Hard Capsules R&D, and Bram Baert, Senior Director of Regulatory Affairs from Lonza, to delve into the intricacies of capsule manufacturing and the evolution of drug delivery technologies. </p> <p>Your grandmother might have told you to “just swallow your medicine,” suggesting that you may have to endure something unpleasant but necessary. Today, however, this old saying might not ring true, as capsules have become ubiquitous in modern medicine. Favored by 44% of consumers, capsules simplify medication intake...
Summit Royalties – Coming Growth Catalysts For This Newly Listed Company Holding A Portfolio of 47 Royalties
<p>Drew Clark, President and CEO of Summit Royalties Ltd. (TSX.V: SUM), joins me to introduce the value proposition and coming growth catalysts from their portfolio of 47 royalty partner projects, mostly focused on gold and silver.</p> <p> </p> <p>We discuss how this Company started off privately when closing the IAMGOLD Royalty Portfolio Acquisition for $17.5M on May 30th, then the acquisition of a royalty at West Red Lake Gold’s Madsen Mine on September 4th. Then on November 5th the company released news of their “go public” transaction with the reverse takeover of Eagle Royalties the prior day on N...
From Confused To Confident: How This Listener Learned You Don’t Need a Whole Bitcoin To Invest and Grow Wealth
<p>Ever felt like you’ve missed the boat on Bitcoin because you can’t afford a whole one?</p><p>You're not alone. As Bitcoin’s price rises, many millennials mistakenly believe they’re priced out. But the real opportunity might lie in something far smaller - <b>sats.</b></p><p>In this myth buster call in episode you will learn: </p>Discover the truth behind the “I can’t afford a whole Bitcoin” myth and how it’s holding you back.Learn how unit bias is steering you toward poor investment choices and how to avoid it.Understand how st...
#72 - Trump Crypto Revolution GENIUS Act Stablecoins & Power
Explore the seismic shift in U.S. crypto policy under Trump’s 2025 administration: a full-throttle pro-crypto agenda anchored by the GENIUS Act. We dive into the banning of a U.S. CBDC, the rise of regulated private stablecoins, and the geopolitics of a “digital dollar” powered by the private market. Learn how this policy supports Circle (USDC), favors issuers tied to Trump, and raises major governance and ethical risks. Can this revolution cement the U.S. as a global crypto power — or will it backfire in a tangle of conflicts of interest?<br /><br />This episode includes AI-generated content.
Episode 3: A View On mRNA Encapsulation
<p>Driving Innovation Through Collaboration: The Future of mRNA Therapies</p> <p>In this episode, we are joined by three experts—Christoph Hein (Fraunhofer IPK), Bernhard Bobusch (FDX Fluid Dynamix), and Sönke Stocker (Lonza)—to explore how advanced fluidics, encapsulation techniques, and a truly collaborative approach are paving the way for potential solid-tumor vaccines now in preclinical trials.</p> <p>When you think about mRNA-based vaccines, have you ever considered the complex route these microscopic instructions must travel to deliver their life-changing code? This journey, essential for the therapy’s success, lies at the core of pharmaceutical research—where the chall...
Why Portugal is not America.
<p>Welcome to Season 4! And what a way to kick off a brand new season. Dylan is joined by best-selling author <b>Richard Zimler</b>, who shares his deeply personal story of moving from the US to Portugal in the early '90s. He opens up about the culture shock of living in Portugal at that time, the kindness of the Portuguese people, and why Portugal feels more like home than America ever did.</p><p><b>FOLLOW OUR GUEST</b></p><b>Richard's website</b><p><b>ABOUT PORTUGAL THE SIMPLE LIFE PODCAST:</b><br/>"Portugal - The simple...
#77 - EigenLayer The Ultimate Guide to Ethereum Restaking for Crypto Passive Income
Welcome to the ultimate guide on the most significant new development in the Ethereum ecosystem: <b>EigenLayer and the Restaking Narrative</b>. This episode breaks down the complex mechanics of <b>Restaking</b> and how it's creating unprecedented opportunities for <b>Crypto Passive Income</b>. We'll explain exactly how <b>EigenLayer</b> works, the role of Actively Validated Services (<b>AVS</b>), and the process of extending Ethereum's trust layer to secure other decentralized protocols. Discover the difference between liquid staking and liquid <b>Restaking</b>, the potential risks (like amplified slashing), and the enormous new sources of <b>Ethereum...
#74 - Monad Mainnet Breakthrough Parallel Execution, MON Tokenomics & Post-ICO Shock
Dive into the launch of Monad’s high-performance Layer-1 mainnet and uncover why its parallel-execution architecture is becoming one of the most discussed breakthroughs in blockchain. We analyze the MON token’s early market dynamics, the impact of the Coinbase ICO, the risks behind the unlocked supply, and the community’s polarized reaction to the airdrop. A deep, captivating overview of a technology promising to reshape the EVM landscape.<br /><br />This episode includes AI-generated content.
#75 - Blockchain AI Investment Crypto Market 2025
Position yourself at the forefront of the crypto market's most explosive sector in 2025 with this investor-focused exploration of AI-blockchain convergence. This podcast analyzes the $24-27 billion AI crypto market, examining top-performing tokens like Bittensor, Fetch.ai, Render, and emerging projects capturing institutional attention. Discover why AI-related cryptocurrency interest has surged 87% in 2025, driven by real-world utility rather than speculation. We break down the investment thesis behind decentralized machine learning networks, GPU marketplace tokens, and AI agent platforms executing billions in autonomous transactions. Learn about the 24 blockchain projects preparing Token Generation Events in Q4 2025, including opportunities in parallel EVM, decentralized AI, and...
Positive Talk with Kevin McDonald and Jaze Bordeaux
<p>Positive Talk with Kevin McDonald and Jaze Bordeaux</p>
Guns, Religion, and Responsibility
<p><b>Guns, Religion, and Responsibility</b></p> <p>Almost 44,000 youth under 18 years old pulled a deer permit in the state of Ohio, which is almost the number of soldiers at Fort Bragg, one of the largest military bases. Of those youth, almost 10,000 reported getting a deer, which is as many people as Eric had in a brigade. If just the youth can do this, why do we spent more than $1 trillion every year on our military? We talk about this, religion, and the lack of morals and responsibility today. We need to get back to the basic premises (like the B...
Netflix & Bill
<p>Will Bain discusses the Employment Rights Bill as it heads back to the Commons.</p><p>Elsewhere, he'll look ahead to the first day of trading for the brand new Magnum Ice Cream Company and check out some of the details in the $72 BILLION deal made by Netflix to buy Warner Bros.</p><p>And, he'll find out what's next for Lando Norris and the new sponsorship deals that could be heading his way after his F1 triumph.</p>
#79 - Crypto Betting Power Is Polymarket the New Oracle of Reality?
Dive into the high-stakes world where data meets dollars. This podcast is your definitive guide to <b>Polymarket</b> and the revolutionary <b>Prediction Markets</b>. We explore how real-money <b>Crypto Betting</b> using stablecoins like <b>USDC</b> is challenging traditional forecasts, polling, and media narratives. Discover the hidden mechanics, ethical debates, and investment opportunities that are shaping the <b>Future of Truth</b>. From elections and major tech launches to bizarre pop-culture outcomes, learn why these markets are becoming the fastest, most accurate signal for what's really going to happen.<br /><br />This episode includes AI-generated content.
Lean Saved Their Factory: Fire Prevention, Inventory Wins & Q4 Strategy | Lean Built - Manufacturing Freedom E123
<p>It's Cyber Monday, and Andrew and Jay dive into year-end strategy, the real cost of Black Friday sales, and why deep discounts often hurt more than they help. They also discuss how lean manufacturing practices literally saved an entire 60,000 sq ft facility after a major fire. </p><p><br></p><p>Elsewhere, Andrew shares the importance of using LinkedIn with intention, how handwritten notes beat (or should be combined with) AI transcription for capturing insights, and why business owners must prioritize end-of-year tasks before the December panic hits. Jay breaks down inventory strategy, shop-floor safety improvements, and the hard t...
The Purpose of Business with QuinnTempest
<p >The true purpose of business isn't growth for growth's sake — it's alignment, sustainability, and impact that lasts.</p> <p >In this powerful first guest episode of The Experienced Entrepreneur, Marissa Lawton sits down with Quinn Tempest, entrepreneur, strategist, and founder of Create Your Purpose®, for a conversation that cuts through the noise of hustle culture and redefines what it means to build a business that truly serves your life.</p> <p >Quinn has been a business owner for more than 13 years, evolving from freelance design to strategic consulting and community leadership for women entrepreneurs. But her path wasn't linear. Aft...
The Power of Looking Back | Lean Built - Manufacturing Freedom E120
<p>In this episode, Andrew and Jay take a walk down memory lane. What starts as Andrew revisiting old shop photos turns into a conversation about the hidden value of reflection in a culture obsessed with constant improvement. The two discuss how looking back fuels gratitude, strengthens company culture, and reminds teams that today’s “normal” was once hard-won progress.</p><p><br></p><p>They also share practical ideas for visualizing improvement over time, from “Lean scoreboards” to posting employee innovations without turning healthy pride into toxic competition. Later, Jay tells the story of an unexpected visit from a high-profi...
