The a16z Show
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon
<p>This conversation with Emil Michael, undersecretary of defense for research and engineering and acting director of the Defense Innovation Unit, was recorded at the a16z American Dynamism Summit in Washington, D.C. Michael walks through how he inherited a department running 14 undefined technology priorities, cut them to six, and made applied AI number one. He also gives the first detailed account of why commercial AI contracts written under the previous administration created a vendor-lock crisis that put active military operations at risk.</p> <p> </p> <p> </p> <p><p>Stay Updated:</p><p>Find a16z on YouTube: Yo...
Palantir CEO Alex Karp on the Zero-Sum AI Race
<p>This conversation with Alex Karp, cofounder and CEO of Palantir, was recorded at the a16z American Dynamism Summit in Washington, D.C. Karp discusses the role of technology in modern warfare, Silicon Valley's obligations to national defense, and why he believes America's single greatest competitive advantage is its ability to cultivate and protect unconventional talent.</p> <p> </p> <p> </p> <p><p>Stay Updated:</p><p>Find a16z on YouTube: YouTube</p><p>Find a16z on X</p><p>Find a16z on LinkedIn</p><p>Listen to the a16z Show on Spotify</p><p>Li...
What It Takes to Clear a Million Crimes a Year with Flock Safety's CEO
<p>In this episode, previously aired on Cheeky Pint, Garrett Langley describes how a stolen gun in his Atlanta neighborhood led him to build Flock Safety, now deployed in more than 6,000 cities and involved in clearing over a million crimes last year. He covers how the product has evolved from license plate cameras to drones, real-time 911 integration, and an AI-powered orchestration layer for city safety.</p> <p> </p> <p>Resources:</p> <p>Follow Garrett Langley on X: https://twitter.com/glangley</p> <p>Follow John Collison on X: https://twitter.com/collision</p> <p>Listen to Cheeky Pint: https://www.you...
The Top 100 Gen AI Consumer Apps
<p>Anish Acharya speaks with Olivia Moore about the latest edition of the a16z Top 100 AI Apps report. They cover why ChatGPT is still 30 times bigger than Claude on web, how the three major platforms are specializing for different users, what global adoption data reveals about cultural attitudes toward AI, and why agents, memory, and voice are about to change everything.</p> <p> </p> <p>Resources:</p> <p>Follow Anish Acharya on X: https://twitter.com/illscience</p> <p>Follow Olivia Moore on X: https://twitter.com/omooretweets</p> <p><p>Stay Updated:</p><p>Find a16z on Y...
Andrew Huberman: Peptides, Sleep Tech, and the End of Obesity
<p>Daisy Wolf speaks with Dr. Andrew Huberman, professor of neurobiology and ophthalmology at Stanford University and host of the Huberman Lab podcast. They discuss how the pandemic sparked a consumer health revolution, the emerging peptide and GLP landscape, what the science actually says about focus drugs, and the neurotechnologies Huberman believes will let us write to our own biology within the next five years.</p> <p> </p> <p>Resources:</p> <p>Follow Andrew Huberman on X: https://twitter.com/hubermanlab</p> <p>Follow Daisy Wolf on X: https://twitter.com/daisydwolf</p> <p><p>Stay Updated:</p><p>Find a...
Atlassian CEO on the SaaS Apocalypse, AI Agents & What Comes Next
<p>Alex Rampell and Erik Torenberg speak with Mike Cannon-Brookes, cofounder and CEO of Atlassian, about how to make sense of the SaaS selloff, why not all software companies face the same AI-driven risks, and how Atlassian is thinking about the shift from records to processes. They also examine the real design challenge of getting everyday users to trust and benefit from AI agents in enterprise workflows.</p> <p> </p> <p>Resources:</p> <p>Follow Alex Rampell on X: https://twitter.com/arampell</p> <p>Follow Erik Torenberg on X: https://twitter.com/eriktorenberg</p> <p>Follow Mike Cannon-Brookes on X: h...
Ben Thompson: Anthropic, the Pentagon, and the Limits of Private Power
<p>In this conversation, previously aired on TBPN, John Coogan and Jordi Hays speak with Ben Thompson, founder of Stratechery, about his essay "Anthropic and Alignment" and the broader collision between AI power and state power that the Anthropic–Department of War standoff revealed.</p> <p> </p> <p>Resources:</p> <p>Follow Ben Thompson on X: https://twitter.com/benthompson</p> <p>Follow John Coogan on X: https://twitter.com/johncoogan</p> <p>Follow Jordi Hays on X: https://twitter.com/jordihays</p> <p>Follow TBPN on X: https://twitter.com/tbpn</p> <p><p>Stay Updated:</p><p>Find a16...
Ambience CEO Nikhil Buduma on AI in Clinical Workflows
<p>a16z general partner Julie Yoo talks with Nikhil Buduma, CEO and cofounder of Ambience Healthcare, to discuss how AI is transforming clinical workflows. They cover the early days of deep learning, why Ambience started by running a medical practice before building a platform company, and what it takes to achieve high clinician adoption rates at major academic medical centers. They also dig into the challenge of building products when AI capabilities change every few months, the real ROI that's finally converting CFOs, and why this might be the moment to reimagine the legacy EHR stack.</p> <p> </p> <p...
Ben Horowitz On What Makes a Great Founder
<p>On the show Long Strange Trip, Sequoia Capital partner Brian Halligan speaks with a16z’s Ben Horowitz about what separates great founder CEOs from everyone else. Ben explains why first-time founders lose confidence, defer too much to senior hires, and let decision debt paralyze their companies. They discuss where founder mode works and where people are taking it too far, why the VP of Sales is the hire founders mess up more than any other, and why Andy Grove's "constructive confrontation" matters more than most CEOs realize. Ben also shares what he's learned working with Zuckerberg, what Jensen Hu...
Chris Dixon: From Quant Trading to Building a16z Crypto
<p>In this feed drop from the Internet History Podcast, host Brian McCullough speaks with Chris Dixon, general partner at a16z, about his path from 1980s hobbyist programmer to one of the most prominent venture capitalists in tech. Chris traces his career from quantitative finance to founding SiteAdvisor, cofounding Founder Collective, starting an early machine learning company, and eventually building a16z's crypto practice from the ground up. They also discuss his framework for spotting unconventional investments, the current state of crypto regulation, and why New York is becoming a serious tech hub.</p> <p> </p> <p>Resources:</p> <p...
